ENSG00000196843


Homo sapiens
bindingARID5Atranscriptiondnareceptorregulationrnadna-templatedariddna-bindingdomainpolymeraseiiimmuneresponseestrogenactivityregulatoryregionsequence-specificsuperfamilyprocessinnatecellularstimulusnucleusnucleoplasmnucleolustranscriptionalrepressorcorepressor

Features
Gene ID: ENSG00000196843
  
Biological name :ARID5A
  
Synonyms : ARID5A / AT-rich interaction domain 5A / Q03989
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q11.2
Gene start: 96536743
Gene end: 96552638
  
Corresponding Affymetrix probe sets: 213138_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000397286
Ensembl peptide - ENSP00000400785
Ensembl peptide - ENSP00000350078
NCBI entrez gene - 10865     See in Manteia.
OMIM - 611583
RefSeq - NM_001319094
RefSeq - NM_001319096
RefSeq - NM_212481
RefSeq - XM_017003185
RefSeq - NM_001319085
RefSeq - NM_001319087
RefSeq - NM_001319092
RefSeq - NM_001319093
RefSeq - XM_011510499
RefSeq - XM_017003183
RefSeq - XM_017003184
RefSeq Peptide - NP_001306022
RefSeq Peptide - NP_001306023
RefSeq Peptide - NP_001306025
RefSeq Peptide - NP_997646
RefSeq Peptide - NP_001306016
RefSeq Peptide - NP_001306021
RefSeq Peptide - NP_001306014
swissprot - Q03989
swissprot - F6Q9D3
Ensembl - ENSG00000196843
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arid5aENSDARG00000077120Danio rerio
 ARID5AENSGALG00000039206Gallus gallus
 Arid5aENSMUSG00000037447Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARID5B / Q14865 / AT-rich interaction domain 5BENSG0000015034737
ARID4B / Q4LE39 / AT-rich interaction domain 4BENSG0000005426719
ARID4A / P29374 / AT-rich interaction domain 4AENSG0000003221915


Protein motifs (from Interpro)
Interpro ID Name
 IPR001606  ARID DNA-binding domain
 IPR036431  ARID DNA-binding domain superfamily


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responseresponse to chemicalresponse to estrogencellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responseresponse to chemicalresponse to estrogencellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responseresponse to chemicalresponse to estrogencellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responseresponse to chemicalresponse to estrogencellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responseresponse to chemicalresponse to estrogencellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responseresponse to chemicalresponse to estrogencellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responseresponse to chemicalresponse to estrogencellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responseresponse to chemicalresponse to estrogencellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responseresponse to chemicalresponse to estrogencellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responseresponse to chemicalresponse to estrogencellular response to stimulusnitrogen componitrogen compound metabolic processbiosynthetic pbiosynthetic processcellular metabcellular metabolic processprimary metaboprimary metabolic processorganic substaorganic substance metabolic processresponse to stresponse to stressimmune responsimmune responseresponse to chresponse to chemicalresponse to esresponse to estrogencellular respocellular response to stimulus
DNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingtranscription coregulator activityprotein bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingtranscription coregulator activityprotein bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingtranscription coregulator activityprotein bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingtranscription coregulator activityprotein bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingtranscription coregulator activityprotein bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingtranscription coregulator activityprotein bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingtranscription coregulator activityprotein bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingtranscription coregulator activityprotein bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingtranscription coregulator activityprotein bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingtranscription coregulator activityprotein bindingDNA-binding transcription faDNA-binding transcription factor activityorganic cyclic compound bindorganic cyclic compound bindingheterocyclic compound bindinheterocyclic compound bindingtranscription coregulator actranscription coregulator activityprotein bindingprotein binding
cellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated TAS
 biological_processGO:0071391 cellular response to estrogen stimulus IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IDA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IC
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003714 transcription corepressor activity IDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IDA
 molecular_functionGO:0030331 estrogen receptor binding IDA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA
 molecular_functionGO:0046965 retinoid X receptor binding IDA
 molecular_functionGO:0046966 thyroid hormone receptor binding IDA
 molecular_functionGO:0050681 androgen receptor binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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