ENSG00000198231


Homo sapiens

Features
Gene ID: ENSG00000198231
  
Biological name :DDX42
  
Synonyms : DDX42 / DEAD-box helicase 42 / Q86XP3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q23.3
Gene start: 63773603
Gene end: 63819317
  
Corresponding Affymetrix probe sets: 1559953_at (Human Genome U133 Plus 2.0 Array)   1559954_s_at (Human Genome U133 Plus 2.0 Array)   201788_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464050
Ensembl peptide - ENSP00000463561
Ensembl peptide - ENSP00000464232
Ensembl peptide - ENSP00000352308
Ensembl peptide - ENSP00000374574
Ensembl peptide - ENSP00000390121
Ensembl peptide - ENSP00000461957
Ensembl peptide - ENSP00000462174
Ensembl peptide - ENSP00000463038
NCBI entrez gene - 11325     See in Manteia.
OMIM - 613369
RefSeq - XM_017024112
RefSeq - NM_007372
RefSeq - NM_203499
RefSeq - XM_006721657
RefSeq - XM_011524259
RefSeq - XM_017024111
RefSeq Peptide - NP_987095
RefSeq Peptide - NP_031398
swissprot - J3KRV0
swissprot - J3KTK9
swissprot - J3QRI2
swissprot - A0A0A0MSJ0
swissprot - Q86XP3
swissprot - J3KRE3
Ensembl - ENSG00000198231
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx42ENSDARG00000037928Danio rerio
 DDX42ENSGALG00000000581Gallus gallus
 Ddx42ENSMUSG00000020705Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DDX17 / Q92841 / DEAD-box helicase 17ENSG0000010020125
DDX5 / P17844 / DEAD-box helicase 5ENSG0000010865424
DDX43 / Q9NXZ2 / DEAD-box helicase 43ENSG0000008000721
DDX53 / Q86TM3 / DEAD-box helicase 53ENSG0000018473519


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0008104 protein localization IDA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:0042981 regulation of apoptotic process IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0015030 Cajal body IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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