ENSG00000198356


Homo sapiens

Features
Gene ID: ENSG00000198356
  
Biological name :ASNA1
  
Synonyms : arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) / ASNA1 / O43681
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.13
Gene start: 12737139
Gene end: 12748323
  
Corresponding Affymetrix probe sets: 202024_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466379
Ensembl peptide - ENSP00000481254
Ensembl peptide - ENSP00000468450
Ensembl peptide - ENSP00000349887
NCBI entrez gene - 439     See in Manteia.
OMIM - 601913
RefSeq - NM_004317
RefSeq Peptide - NP_004308
swissprot - A0A087WXS7
swissprot - K7ERW9
swissprot - O43681
Ensembl - ENSG00000198356
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 asna1ENSDARG00000018190Danio rerio
 Asna1ENSMUSG00000052456Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR016300  Arsenical pump ATPase, ArsA/GET3
 IPR025723  Anion-transporting ATPase-like domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027542  Arsenical pump ATPase, ArsA/GET3, eukaryotic


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015700 arsenite transport IEA
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 biological_processGO:0045048 protein insertion into ER membrane IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005215 transporter activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015105 arsenite transmembrane transporter activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
XBP1(S) activates chaperone genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000106803 P60468 / SEC61B / Sec61 translocon beta subunit  / reaction
 ENSG00000120742 SERP1 / Q9Y6X1 / stress associated endoplasmic reticulum protein 1  / reaction
 ENSG00000058262 P61619 / SEC61A1 / Sec61 translocon alpha 1 subunit  / reaction
 ENSG00000065665 Q9H9S3 / SEC61A2 / Sec61 translocon alpha 2 subunit  / reaction
 ENSG00000008952 SEC62 / Q99442 / SEC62 homolog, preprotein translocation factor  / reaction
 ENSG00000132432 P60059 / SEC61G / Sec61 translocon gamma subunit  / reaction
 ENSG00000025796 SEC63 / Q9UGP8 / SEC63 homolog, protein translocation regulator  / reaction






 

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