ENSG00000198585


Homo sapiens

Features
Gene ID: ENSG00000198585
  
Biological name :NUDT16
  
Synonyms : nudix hydrolase 16 / NUDT16 / Q96DE0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q22.1
Gene start: 131381671
Gene end: 131388830
  
Corresponding Affymetrix probe sets: 228341_at (Human Genome U133 Plus 2.0 Array)   235002_at (Human Genome U133 Plus 2.0 Array)   235054_at (Human Genome U133 Plus 2.0 Array)   238515_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000422375
Ensembl peptide - ENSP00000429274
Ensembl peptide - ENSP00000440230
NCBI entrez gene - 131870     See in Manteia.
OMIM - 617381
RefSeq - NM_001171906
RefSeq - NM_001171905
RefSeq - NM_152395
RefSeq Peptide - NP_001165376
RefSeq Peptide - NP_001165377
RefSeq Peptide - NP_689608
swissprot - Q96DE0
Ensembl - ENSG00000198585
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:103759ENSDARG00000019503Danio rerio
 1700080E11RikENSMUSG00000032566Mus musculus
 Nudt16ENSMUSG00000032565Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BRJ7 / NUDT16L1 / nudix hydrolase 16 like 1ENSG0000016810136


Protein motifs (from Interpro)
Interpro ID Name
 IPR000086  NUDIX hydrolase domain
 IPR015797  NUDIX hydrolase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006382 adenosine to inosine editing IMP
 biological_processGO:0006402 mRNA catabolic process IDA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0009117 nucleotide metabolic process IEA
 biological_processGO:0016077 snoRNA catabolic process IDA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0034656 nucleobase-containing small molecule catabolic process TAS
 biological_processGO:0035863 dITP catabolic process ISS
 biological_processGO:0046709 IDP catabolic process IDA
 biological_processGO:0090068 positive regulation of cell cycle process IMP
 biological_processGO:1901639 XDP catabolic process IDA
 biological_processGO:2000233 negative regulation of rRNA processing ISS
 biological_processGO:2000781 positive regulation of double-strand break repair IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IDA
 molecular_functionGO:0005525 GTP binding IDA
 molecular_functionGO:0008235 metalloexopeptidase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030145 manganese ion binding IDA
 molecular_functionGO:0030515 snoRNA binding IDA
 molecular_functionGO:0035870 dITP diphosphatase activity ISS
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050072 m7G(5")pppN diphosphatase activity IDA
 molecular_functionGO:0050897 cobalt ion binding IDA
 molecular_functionGO:0097383 dIDP diphosphatase activity EXP
 molecular_functionGO:0098519 nucleotide phosphatase activity, acting on free nucleotides IDA
 molecular_functionGO:1901640 XTP binding IDA
 molecular_functionGO:1901641 ITP binding IDA
 molecular_functionGO:1990003 IDP phosphatase activity EXP


Pathways (from Reactome)
Pathway description
Phosphate bond hydrolysis by NUDT proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000198585 NUDT16 / Q96DE0 / nudix hydrolase 16  / complex






 

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