ENSG00000204525
Homo sapiens antigen HLA-C mhc membrane class alpha presentation peptide processing signaling pathway immunoglobulin-like protein immune via interferon golgi chain domain i-like recognition-like superfamily process exogenous response neutrophil degranulation endoplasmic reticulum cell vesicle
Features Gene ID: ENSG00000204525 Biological name :HLA-C Synonyms : HLA-C / major histocompatibility complex, class I, C / P10321 Possible biological names infered from orthology : Species: Homo sapiens Chr. number: 6 Strand: -1 Band: p21.33 Gene start: 31268749 Gene end: 31272130 Corresponding Affymetrix probe sets: 208812_x_at (Human Genome U133 Plus 2.0 Array) 211799_x_at (Human Genome U133 Plus 2.0 Array) 214459_x_at (Human Genome U133 Plus 2.0 Array) 216526_x_at (Human Genome U133 Plus 2.0 Array) Cross references: Ensembl peptide - ENSP00000365412 Ensembl peptide - ENSP00000492782 Ensembl peptide - ENSP00000400410 Ensembl peptide - ENSP00000372819 Ensembl peptide - ENSP00000365402 NCBI entrez gene - 3107
See in Manteia .
OMIM - 142840 RefSeq - NM_002117 RefSeq Peptide - NP_002108 swissprot - A0A140T9E1 swissprot - F8W9Z8 swissprot - P10321 swissprot - A2AEA2 swissprot - Q6R739 swissprot - A0A1W2PRU9 Ensembl - ENSG00000204525 Related genetic diseases (OMIM): 177900 - {Psoriasis susceptibility 1}, 177900 609423 - {HIV-1 viremia, susceptibility to}, 609423
See expression report in BioGPS See gene description in Wikigenes See gene description in GeneCards See co-cited genes in PubMed Ortholog prediction (from Ensembl )
Paralog prediction (from Ensembl ) HLA-B / P30480 / P30486 / Q29836 / Q31610 / Q31612 / P01889 / major histocompatibility complex, class I, B ENSG00000234745 86 HLA-A / P04439 / P13746 / P16188 / major histocompatibility complex, class I, A ENSG00000206503 81 HLA-F / P30511 / major histocompatibility complex, class I, F ENSG00000204642 75 HLA-E / major histocompatibility complex, class I, E ENSG00000204592 74 HLA-G / P17693 / major histocompatibility complex, class I, G ENSG00000204632 74
Protein motifs (from Interpro ) IPR001039 MHC class I alpha chain, alpha1 alpha2 domains IPR003597 Immunoglobulin C1-set IPR007110 Immunoglobulin-like domain IPR010579 MHC class I, alpha chain, C-terminal IPR011161 MHC class I-like antigen recognition-like IPR011162 MHC classes I/II-like antigen recognition protein IPR013783 Immunoglobulin-like fold IPR036179 Immunoglobulin-like domain superfamily IPR037055 MHC class I-like antigen recognition-like superfamily
Gene Ontology (GO ) antigen processing and presentation immune response interspecies interaction between organisms establishment of localization cell activation immune effector process response to stress cell communication response to chemical cellular response to stimulus antigen processing and presentation immune response interspecies interaction between organisms establishment of localization cell activation immune effector process response to stress cell communication response to chemical cellular response to stimulus antigen processing and presentation immune response interspecies interaction between organisms establishment of localization cell activation immune effector process response to stress cell communication response to chemical cellular response to stimulus antigen processing and presentation immune response interspecies interaction between organisms establishment of localization cell activation immune effector process response to stress cell communication response to chemical cellular response to stimulus antigen processing and presentation immune response interspecies interaction between organisms establishment of localization cell activation immune effector process response to stress cell communication response to chemical cellular response to stimulus antigen processing and presentation immune response interspecies interaction between organisms establishment of localization cell activation immune effector process response to stress cell communication response to chemical cellular response to stimulus antigen processing and presentation immune response interspecies interaction between organisms establishment of localization cell activation immune effector process response to stress cell communication response to chemical cellular response to stimulus antigen processing and presentation immune response interspecies interaction between organisms establishment of localization cell activation immune effector process response to stress cell communication response to chemical cellular response to stimulus antigen processing and presentation immune response interspecies interaction between organisms establishment of localization cell activation immune effector process response to stress cell communication response to chemical cellular response to stimulus antigen processing and presentation immune response interspecies interaction between organisms establishment of localization cell activation immune effector process response to stress cell communication response to chemical cellular response to stimulus antigen procesantigen processing and presentation immune responsimmune response interspecies iinterspecies interaction between organisms establishment establishment of localization cell activatiocell activation immune effectoimmune effector process response to stresponse to stress cell communicacell communication response to chresponse to chemical cellular respocellular response to stimulus protein binding antigen binding amide binding protein binding antigen binding amide binding protein binding antigen binding amide binding protein binding antigen binding amide binding protein binding antigen binding amide binding protein binding antigen binding amide binding protein binding antigen binding amide binding protein binding antigen binding amide binding protein binding antigen binding amide binding protein binding antigen binding amide binding protein bindingprotein binding antigen bindingantigen binding amide bindingamide binding cell membrane organelle protein-containing complex extracellular region cell membrane organelle protein-containing complex extracellular region cell membrane organelle protein-containing complex extracellular region cell membrane organelle protein-containing complex extracellular region cell membrane organelle protein-containing complex extracellular region cell membrane organelle protein-containing complex extracellular region cell membrane organelle protein-containing complex extracellular region cell membrane organelle protein-containing complex extracellular region cell membrane organelle protein-containing complex extracellular region cell membrane organelle protein-containing complex extracellular region cellcell membranemembrane organelleorganelle protein-containing complexprotein-containing complex extracellular regionextracellular region
Pathways (from Reactome )
Phenotype (from MGI , Zfin or HPO )
No match
Interacting proteins (from Reactome )No match
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