ENSG00000205629


Homo sapiens

Features
Gene ID: ENSG00000205629
  
Biological name :LCMT1
  
Synonyms : LCMT1 / leucine carboxyl methyltransferase 1 / Q9UIC8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p12.1
Gene start: 25111729
Gene end: 25178231
  
Corresponding Affymetrix probe sets: 221515_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000461754
Ensembl peptide - ENSP00000459851
Ensembl peptide - ENSP00000461100
Ensembl peptide - ENSP00000370349
Ensembl peptide - ENSP00000370353
Ensembl peptide - ENSP00000382021
Ensembl peptide - ENSP00000457741
Ensembl peptide - ENSP00000459604
NCBI entrez gene - 51451     See in Manteia.
OMIM - 610286
RefSeq - XM_011545864
RefSeq - NM_001032391
RefSeq - NM_016309
RefSeq - XM_005255354
RefSeq - XM_011545862
RefSeq Peptide - NP_001027563
RefSeq Peptide - NP_057393
swissprot - H3BUP7
swissprot - H7BYF0
swissprot - I3L2E3
swissprot - I3L2Q8
swissprot - I3L537
swissprot - I3L4A2
swissprot - Q9UIC8
Ensembl - ENSG00000205629
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lcmt1ENSDARG00000045140Danio rerio
 LCMT1ENSGALG00000005973Gallus gallus
 Lcmt1ENSMUSG00000030763Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LCMT2 / O60294 / leucine carboxyl methyltransferase 2ENSG0000016880633


Protein motifs (from Interpro)
Interpro ID Name
 IPR007213  Methyltransferase Ppm1/Ppm2/Tcmp
 IPR016651  Leucine carboxyl methyltransferase 1, LCMT1
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0006464 cellular protein modification process TAS
 biological_processGO:0006479 protein methylation IMP
 biological_processGO:0006481 C-terminal protein methylation IDA
 biological_processGO:0010906 regulation of glucose metabolic process IEA
 biological_processGO:0031333 negative regulation of protein complex assembly IMP
 biological_processGO:0032259 methylation IEA
 biological_processGO:0042981 regulation of apoptotic process IMP
 biological_processGO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint IMP
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0003880 protein C-terminal carboxyl O-methyltransferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008276 protein methyltransferase activity IEA
 molecular_functionGO:0008757 S-adenosylmethionine-dependent methyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018423 protein C-terminal leucine carboxyl O-methyltransferase activity TAS


Pathways (from Reactome)
Pathway description
Cyclin A/B1/B2 associated events during G2/M transition


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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