ENSG00000205937


Homo sapiens

Features
Gene ID: ENSG00000205937
  
Biological name :RNPS1
  
Synonyms : Q15287 / RNA binding protein with serine rich domain 1 / RNPS1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p13.3
Gene start: 2253116
Gene end: 2268412
  
Corresponding Affymetrix probe sets: 200060_s_at (Human Genome U133 Plus 2.0 Array)   207939_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000457820
Ensembl peptide - ENSP00000457723
Ensembl peptide - ENSP00000457987
Ensembl peptide - ENSP00000301730
Ensembl peptide - ENSP00000315859
Ensembl peptide - ENSP00000380275
Ensembl peptide - ENSP00000454461
Ensembl peptide - ENSP00000454513
Ensembl peptide - ENSP00000454867
Ensembl peptide - ENSP00000455013
Ensembl peptide - ENSP00000455195
Ensembl peptide - ENSP00000455306
Ensembl peptide - ENSP00000455379
Ensembl peptide - ENSP00000456283
Ensembl peptide - ENSP00000456352
Ensembl peptide - ENSP00000457110
Ensembl peptide - ENSP00000457296
Ensembl peptide - ENSP00000457338
Ensembl peptide - ENSP00000457378
Ensembl peptide - ENSP00000457618
Ensembl peptide - ENSP00000457690
NCBI entrez gene - 10921     See in Manteia.
OMIM - 606447
RefSeq - NM_001286626
RefSeq - NM_001286625
RefSeq - NM_001286627
RefSeq - NM_006711
RefSeq - NM_080594
RefSeq - XM_005255048
RefSeq - XM_005255049
RefSeq - XM_017022874
RefSeq Peptide - NP_001273556
RefSeq Peptide - NP_001273554
RefSeq Peptide - NP_001273555
RefSeq Peptide - NP_006702
RefSeq Peptide - NP_542161
swissprot - H3BUL0
swissprot - H3BV80
swissprot - D3DU92
swissprot - Q15287
swissprot - H3BMM9
swissprot - H3BMS0
swissprot - H3BNI3
swissprot - H3BNU7
swissprot - H3BP82
swissprot - H3BPG5
swissprot - H3BTC0
swissprot - H3BRK4
swissprot - H3BTR6
swissprot - H3BTV0
swissprot - H3BTY0
swissprot - H3BUG0
Ensembl - ENSG00000205937
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FO904885.3ENSDARG00000116743Danio rerio
 RNPS1ENSGALG00000009288Gallus gallus
 Rnps1ENSMUSG00000034681Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR014010  REJ domain
 IPR034201  RNPS1, RNA recognition motif
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IMP
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006351 transcription, DNA-templated TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0008380 RNA splicing TAS
 biological_processGO:0031124 mRNA 3"-end processing TAS
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0048025 negative regulation of mRNA splicing, via spliceosome IDA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0035145 exon-exon junction complex TAS
 cellular_componentGO:0061574 ASAP complex IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3-end processing
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000108349 CASC3 / O15234 / cancer susceptibility 3  / complex
 ENSG00000125351 UPF3B / Q9BZI7 / UPF3B, regulator of nonsense mediated mRNA decay  / complex
 ENSG00000141543 EIF4A3 / P38919 / eukaryotic translation initiation factor 4A3  / complex
 ENSG00000111196 MAGOHB / Q96A72 / mago homolog B, exon junction complex core component  / complex
 ENSG00000169062 UPF3A / Q9H1J1 / UPF3A, regulator of nonsense mediated mRNA decay  / complex
 ENSG00000151461 UPF2 / Q9HAU5 / UPF2, regulator of nonsense mediated mRNA decay  / complex
 ENSG00000162385 MAGOH / P61326 / mago homolog, exon junction complex core component  / complex
 ENSG00000265241 RBM8A / Q9Y5S9 / RNA binding motif protein 8A  / complex






 

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