ENSG00000214456


Homo sapiens
regulationPLIN5lipidprocesstriglyceridelipasestoragecatabolicfattyacidbeta-oxidationmitochondrionactivitybindingperilipinbiosyntheticsequesteringparticleorganizationperoxisomeproliferatoractivatedreceptorsignalingpathwaylocalizationreactiveoxygenspeciesmetaboliccytoplasm

Features
Gene ID: ENSG00000214456
  
Biological name :PLIN5
  
Synonyms : perilipin 5 / PLIN5 / Q00G26
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 4522531
Gene end: 4535224
  
Corresponding Affymetrix probe sets: 1560456_at (Human Genome U133 Plus 2.0 Array)   1560457_x_at (Human Genome U133 Plus 2.0 Array)   1568666_at (Human Genome U133 Plus 2.0 Array)   1568667_s_at (Human Genome U133 Plus 2.0 Array)   238019_at (Human Genome U133 Plus 2.0 Array)   241368_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464926
Ensembl peptide - ENSP00000468027
Ensembl peptide - ENSP00000371272
NCBI entrez gene - 440503     See in Manteia.
OMIM - 613248
RefSeq - NM_001013706
RefSeq Peptide - NP_001013728
swissprot - K7EIX1
swissprot - Q00G26
Ensembl - ENSG00000214456
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plin6ENSDARG00000076844Danio rerio
 Plin5ENSMUSG00000011305Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLIN3 / O60664 / perilipin 3ENSG0000010535536
PLIN2 / Q99541 / perilipin 2ENSG0000014787231
PLIN1 / O60240 / perilipin 1ENSG0000016681923
PLIN4 / Q96Q06 / perilipin 4ENSG0000016767623


Protein motifs (from Interpro)
Interpro ID Name
 IPR004279  Perilipin


Gene Ontology (GO)
biosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of biological qualitycatabolic processsmall molecule metabolic processoxidation-reduction processcellular component organizationcell communicationcellular response to stimuluscellular localizationregulation of molecular functionbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of biological qualitycatabolic processsmall molecule metabolic processoxidation-reduction processcellular component organizationcell communicationcellular response to stimuluscellular localizationregulation of molecular functionbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of biological qualitycatabolic processsmall molecule metabolic processoxidation-reduction processcellular component organizationcell communicationcellular response to stimuluscellular localizationregulation of molecular functionbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of biological qualitycatabolic processsmall molecule metabolic processoxidation-reduction processcellular component organizationcell communicationcellular response to stimuluscellular localizationregulation of molecular functionbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of biological qualitycatabolic processsmall molecule metabolic processoxidation-reduction processcellular component organizationcell communicationcellular response to stimuluscellular localizationregulation of molecular functionbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of biological qualitycatabolic processsmall molecule metabolic processoxidation-reduction processcellular component organizationcell communicationcellular response to stimuluscellular localizationregulation of molecular functionbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of biological qualitycatabolic processsmall molecule metabolic processoxidation-reduction processcellular component organizationcell communicationcellular response to stimuluscellular localizationregulation of molecular functionbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of biological qualitycatabolic processsmall molecule metabolic processoxidation-reduction processcellular component organizationcell communicationcellular response to stimuluscellular localizationregulation of molecular functionbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of biological qualitycatabolic processsmall molecule metabolic processoxidation-reduction processcellular component organizationcell communicationcellular response to stimuluscellular localizationregulation of molecular functionbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of biological qualitycatabolic processsmall molecule metabolic processoxidation-reduction processcellular component organizationcell communicationcellular response to stimuluscellular localizationregulation of molecular functionbiosynthetbiosynthetic processcellular mcellular metabolic processprimary meprimary metabolic processorganic suorganic substance metabolic processmacromolecmacromolecule localizationregulationregulation of biological qualitycatabolic catabolic processsmall molesmall molecule metabolic processoxidation-oxidation-reduction processcellular ccellular component organizationcell commucell communicationcellular rcellular response to stimuluscellular lcellular localizationregulationregulation of molecular function
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0010867 positive regulation of triglyceride biosynthetic process IEA
 biological_processGO:0010884 positive regulation of lipid storage IEA
 biological_processGO:0010890 positive regulation of sequestering of triglyceride IEA
 biological_processGO:0010897 negative regulation of triglyceride catabolic process IEA
 biological_processGO:0019915 lipid storage IEA
 biological_processGO:0031999 negative regulation of fatty acid beta-oxidation IEA
 biological_processGO:0032000 positive regulation of fatty acid beta-oxidation IEA
 biological_processGO:0034389 lipid particle organization IEA
 biological_processGO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway IEA
 biological_processGO:0050995 negative regulation of lipid catabolic process IEA
 biological_processGO:0051646 mitochondrion localization IEA
 biological_processGO:0060192 negative regulation of lipase activity IEA
 biological_processGO:0060193 positive regulation of lipase activity IEA
 biological_processGO:2000378 negative regulation of reactive oxygen species metabolic process IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion ISS
 cellular_componentGO:0005811 lipid droplet ISS
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0035473 lipase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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