ENSG00000225968


Homo sapiens

Features
Gene ID: ENSG00000225968
  
Biological name :ELFN1
  
Synonyms : ELFN1 / extracellular leucine rich repeat and fibronectin type III domain containing 1 / P0C7U0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p22.3
Gene start: 1688119
Gene end: 1747954
  
Corresponding Affymetrix probe sets: 229581_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000456548
Ensembl peptide - ENSP00000457193
NCBI entrez gene - 392617     See in Manteia.
OMIM - 614964
RefSeq - XM_017012203
RefSeq - NM_001128636
RefSeq - XM_011515398
RefSeq - XM_011515401
RefSeq - XM_006715725
RefSeq - XM_006715726
RefSeq - XM_006715727
RefSeq - XM_011515397
RefSeq Peptide - NP_001122108
swissprot - P0C7U0
Ensembl - ENSG00000225968
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 elfn1bENSDARG00000074372Danio rerio
 ELFN1ENSGALG00000004209Gallus gallus
 Elfn1ENSMUSG00000048988Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ELFN2 / Q5R3F8 / extracellular leucine rich repeat and fibronectin type III domain containing 2ENSG0000016689748
O94933 / SLITRK3 / SLIT and NTRK like family member 3ENSG0000012187114
O94991 / SLITRK5 / SLIT and NTRK like family member 5ENSG0000016530014
Q9H5Y7 / SLITRK6 / SLIT and NTRK like family member 6ENSG0000018456414
Q8IW52 / SLITRK4 / SLIT and NTRK like family member 4ENSG0000017954213
O96002 / Q9H156 / SLITRK2 / SLIT and NTRK like family member 2ENSG0000018598513
Q96PX8 / SLITRK1 / SLIT and NTRK like family member 1ENSG0000017823511
LRRC19 / Q9H756 / leucine rich repeat containing 19ENSG000001844349


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR013783  Immunoglobulin-like fold
 IPR021157  Cytochrome c1, transmembrane anchor, C-terminal
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010923 negative regulation of phosphatase activity IDA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0050808 synapse organization ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0060076 excitatory synapse ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004864 protein phosphatase inhibitor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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