ENSG00000247746


Homo sapiens

Features
Gene ID: ENSG00000247746
  
Biological name :USP51
  
Synonyms : Q70EK9 / ubiquitin specific peptidase 51 / USP51
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: p11.21
Gene start: 55484616
Gene end: 55489202
  
Corresponding Affymetrix probe sets: 229278_at (Human Genome U133 Plus 2.0 Array)   237247_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000490435
Ensembl peptide - ENSP00000423333
NCBI entrez gene - 158880     See in Manteia.
RefSeq - XM_017029301
RefSeq - NM_201286
RefSeq - XM_017029299
RefSeq - XM_017029300
RefSeq Peptide - NP_958443
swissprot - A0A1B0GVA6
swissprot - Q70EK9
Ensembl - ENSG00000247746
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp22ENSDARG00000040407Danio rerio
 ENSGALG00000029817Gallus gallus
 Usp51ENSMUSG00000067215Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
USP22 / Q9UPT9 / ubiquitin specific peptidase 22ENSG0000012442252
A6NNY8 / USP27X / ubiquitin specific peptidase 27, X-linkedENSG0000027382044
USP44 / Q9H0E7 / ubiquitin specific peptidase 44ENSG0000013601421
USP3 / Q9Y6I4 / ubiquitin specific peptidase 3ENSG0000014045520
USP49 / Q70CQ1 / ubiquitin specific peptidase 49ENSG0000016466320
USP42 / Q9H9J4 / ubiquitin specific peptidase 42ENSG0000010634615
USP36 / Q9P275 / ubiquitin specific peptidase 36ENSG0000005548314
Q6R6M4 / USP17L2 / ubiquitin specific peptidase 17-like family member 2ENSG0000022344314
C9J2P7 / USP17L15 / ubiquitin specific peptidase 17-like family member 15ENSG0000022356914
A6NCW0 / USP17L3 / ubiquitin specific peptidase 17-like family member 3ENSG0000022532714
A8MUK1 / USP17L5 / ubiquitin specific peptidase 17-like family member 5ENSG0000022714014
C9JPN9 / USP17L12 / ubiquitin specific peptidase 17-like family member 12ENSG0000022755114
Q0WX57 / USP17L30 / ubiquitin specific peptidase 17-like family member 30ENSG0000022885614
Q0WX57 / USP17L26 / ubiquitin specific peptidase 17-like family member 26ENSG0000022957914
Q0WX57 / USP17L25 / ubiquitin specific peptidase 17-like family member 25ENSG0000023043014
Q7RTZ2 / USP17L1 / ubiquitin specific peptidase 17-like family member 1ENSG0000023054914
Q0WX57 / USP17L28 / ubiquitin specific peptidase 17-like family member 28ENSG0000023105114
C9JJH3 / USP17L10 / ubiquitin specific peptidase 17-like family member 10ENSG0000023139614
Q0WX57 / USP17L29 / ubiquitin specific peptidase 17-like family member 29ENSG0000023163714
Q0WX57 / USP17L24 / ubiquitin specific peptidase 17-like family member 24ENSG0000023226414


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR001607  Zinc finger, UBP-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain
 IPR033383  Ubiquitin-specific peptidase 51


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0010564 regulation of cell cycle process IMP
 biological_processGO:0010569 regulation of double-strand break repair via homologous recombination IMP
 biological_processGO:0016578 histone deubiquitination IMP
 biological_processGO:0016579 protein deubiquitination IEA
 biological_processGO:2001020 regulation of response to DNA damage stimulus IDA
 biological_processGO:2001032 regulation of double-strand break repair via nonhomologous end joining IMP
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IDA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0042393 histone binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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