ENSG00000256043


Homo sapiens

Features
Gene ID: ENSG00000256043
  
Biological name :CTSO
  
Synonyms : cathepsin O / CTSO / P43234
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q32.1
Gene start: 155924118
Gene end: 155953917
  
Corresponding Affymetrix probe sets: 203758_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000414904
NCBI entrez gene - 1519     See in Manteia.
OMIM - 600550
RefSeq - NM_001334
RefSeq Peptide - NP_001325
swissprot - P43234
Ensembl - ENSG00000256043
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctsoENSDARG00000052855Danio rerio
 CTSOENSGALG00000009373Gallus gallus
 CtsoENSMUSG00000028015Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CTSC / P53634 / cathepsin CENSG0000010986126
CTSZ / Q9UBR2 / cathepsin ZENSG0000010116022
Q9GZM7 / TINAGL1 / tubulointerstitial nephritis antigen like 1ENSG0000014291022
TINAG / Q9UJW2 / tubulointerstitial nephritis antigenENSG0000013725121
CTSB / P07858 / cathepsin BENSG0000016473319


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR000668  Peptidase C1A, papain C-terminal
 IPR013128  Peptidase C1A
 IPR025660  Cysteine peptidase, histidine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis TAS
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IBA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005764 lysosome IBA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity TAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
MHC class II antigen presentation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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