ENSG00000267618


Homo sapiens
dnarepairzincfingerrecombinationproteindomainbindingring-typeringfyvephd-typerad-likec-terminalreca-likeatp-bindingp-loopcontainingnucleosidetriphosphatehydrolasesapsuperfamilyatpdna-dependentatpaseactivity

Features
Gene ID: ENSG00000267618
  
Biological name :AC004223.3
  
Synonyms : AC004223.3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q12
Gene start: 35011349
Gene end: 35121493
  
Corresponding Affymetrix probe sets: 1552649_a_at (Human Genome U133 Plus 2.0 Array)   1552651_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464799
Ensembl peptide - ENSP00000466834
Ensembl peptide - ENSP00000467986
swissprot - K7EIL6
swissprot - K7EN88
swissprot - K7EQU8
Ensembl - ENSG00000267618
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rfflENSDARG00000042833Danio rerio
 zgc:171740ENSDARG00000056244Danio rerio
 RFFLENSGALG00000002225Gallus gallus
 RfflENSMUSG00000020696Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RFFL / Q8WZ73 / ring finger and FYVE like domain containing E3 ubiquitin protein ligaseENSG0000009287141
RNF34 / Q969K3 / ring finger protein 34ENSG0000017063331


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013632  DNA recombination and repair protein Rad51-like, C-terminal
 IPR020588  DNA recombination and repair protein RecA-like, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036361  SAP domain superfamily


Gene Ontology (GO)
nitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusnitrogen compound metabnitrogen compound metabolic processresponse to stressresponse to stresscellular metabolic proccellular metabolic processprimary metabolic proceprimary metabolic processorganic substance metaborganic substance metabolic processcellular response to stcellular response to stimulus
organic cyclic compound bindingheterocyclic compound bindingion bindingcarbohydrate derivative bindingsmall molecule bindingdrug bindinghydrolase activityorganic cyclic compound bindingheterocyclic compound bindingion bindingcarbohydrate derivative bindingsmall molecule bindingdrug bindinghydrolase activityorganic cyclic compound bindingheterocyclic compound bindingion bindingcarbohydrate derivative bindingsmall molecule bindingdrug bindinghydrolase activityorganic cyclic compound bindingheterocyclic compound bindingion bindingcarbohydrate derivative bindingsmall molecule bindingdrug bindinghydrolase activityorganic cyclic compound bindingheterocyclic compound bindingion bindingcarbohydrate derivative bindingsmall molecule bindingdrug bindinghydrolase activityorganic cyclic compound bindingheterocyclic compound bindingion bindingcarbohydrate derivative bindingsmall molecule bindingdrug bindinghydrolase activityorganic cyclic compound bindingheterocyclic compound bindingion bindingcarbohydrate derivative bindingsmall molecule bindingdrug bindinghydrolase activityorganic cyclic compound bindingheterocyclic compound bindingion bindingcarbohydrate derivative bindingsmall molecule bindingdrug bindinghydrolase activityorganic cyclic compound bindingheterocyclic compound bindingion bindingcarbohydrate derivative bindingsmall molecule bindingdrug bindinghydrolase activityorganic cyclic compound bindingheterocyclic compound bindingion bindingcarbohydrate derivative bindingsmall molecule bindingdrug bindinghydrolase activityorganic cyclic compoorganic cyclic compound bindingheterocyclic compounheterocyclic compound bindingion bindingion bindingcarbohydrate derivatcarbohydrate derivative bindingsmall molecule bindismall molecule bindingdrug bindingdrug bindinghydrolase activityhydrolase activity
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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