ENSGALG00000000259


Gallus gallus

Features
Gene ID: ENSGALG00000000259
  
Biological name :PSMF1
  
Synonyms : proteasome inhibitor subunit 1 / PSMF1
  
Possible biological names infered from orthology : proteasome (prosome, macropain) inhibitor subunit 1 / Q8BHL8 / Q92530
  
Species: Gallus gallus
  
Chr. number: 20
Strand: -1
Band:
Gene start: 10068516
Gene end: 10074329
  
Corresponding Affymetrix probe sets: GgaAffx.12524.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000063747
Ensembl peptide - ENSGALP00000000338
NCBI entrez gene - 430115     See in Manteia.
RefSeq - NM_001031582
RefSeq Peptide - NP_001026753
swissprot - Q5ZJL3
swissprot - A0A1L1RY23
Ensembl - ENSGALG00000000259
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 psmf1ENSDARG00000022652Danio rerio
 PSMF1ENSG00000125818Homo sapiens
 Psmf1ENSMUSG00000032869Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013886  PI31 proteasome regulator, C-terminal
 IPR021625  PI31 proteasome regulator, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:1901799 negative regulation of proteasomal protein catabolic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0070628 proteasome binding IEA


Pathways (from Reactome)
Pathway description
GLI3 is processed to GLI3R by the proteasome
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
Regulation of RUNX3 expression and activity
MAPK6/MAPK4 signaling
TNFR2 non-canonical NF-kB pathway
Neddylation
SCF-beta-TrCP mediated degradation of Emi1
Autodegradation of Cdh1 by Cdh1:APC/C
Regulation of PTEN stability and activity
Regulation of RUNX2 expression and activity
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Autodegradation of the E3 ubiquitin ligase COP1
FCERI mediated NF-kB activation
Separation of Sister Chromatids
Degradation of beta-catenin by the destruction complex
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Cross-presentation of soluble exogenous antigens (endosomes)
AUF1 (hnRNP D0) binds and destabilizes mRNA
ABC-family proteins mediated transport
Activation of NF-kappaB in B cells
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
APC/C:Cdc20 mediated degradation of Securin
Antigen processing: Ubiquitination & Proteasome degradation
Asymmetric localization of PCP proteins
CLEC7A (Dectin-1) signaling
CDT1 association with the CDC6:ORC:origin complex
CDK-mediated phosphorylation and removal of Cdc6
Degradation of GLI1 by the proteasome
Degradation of DVL
Degradation of AXIN
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
Downstream TCR signaling
Hedgehog on state
Hedgehog ligand biogenesis
Interleukin-1 signaling
Orc1 removal from chromatin
Regulation of RAS by GAPs
Regulation of ornithine decarboxylase (ODC)
SCF(Skp2)-mediated degradation of p27/p21
Ub-specific processing proteases
UCH proteinases
Ubiquitin-dependent degradation of Cyclin D1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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