ENSGALG00000000977


Gallus gallus
bindingMAPKAP1proteinsignalingphosphatidylinositol--bisphosphatedomainsinkinasetorcregulationrasaktsapk-interactingpleckstrin-homologymiddlecrimn-terminalestablishmentmaintenanceactincytoskeletonpolaritystress-activatedcascadesignaltransductionnucleoplasmcytoplasmgolgiapparatus

Features
Gene ID: ENSGALG00000000977
  
Biological name :MAPKAP1
  
Synonyms : MAPKAP1 / Q9W6S3 / Target of rapamycin complex 2 subunit MAPKAP1
  
Possible biological names infered from orthology : mitogen-activated protein kinase associated protein 1 / Q8BKH7 / Q9BPZ7
  
Species: Gallus gallus
  
Chr. number: 17
Strand: -1
Band:
Gene start: 10126237
Gene end: 10210950
  
Corresponding Affymetrix probe sets: Gga.1093.1.S1_at (Chicken Array)   Gga.1093.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001441
NCBI entrez gene - 395627     See in Manteia.
RefSeq - XM_015279322
RefSeq - NM_204826
RefSeq - XM_015279320
RefSeq - XM_015279321
RefSeq - XM_015279319
RefSeq Peptide - NP_990157
swissprot - Q9W6S3
Ensembl - ENSGALG00000000977
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mapkap1ENSDARG00000091777Danio rerio
 Q9BPZ7ENSG00000119487Homo sapiens
 Q8BKH7ENSMUSG00000038696Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR031313  SAPK-interacting protein 1, Pleckstrin-homology domain
 IPR031567  Sin1, middle CRIM domain
 IPR032679  Sin1, N-terminal


Gene Ontology (GO)
cellular component organizationestablishment or maintenance of cell polarityactin filament-based processresponse to stresscell communicationcellular response to stimuluscellular component organizationestablishment or maintenance of cell polarityactin filament-based processresponse to stresscell communicationcellular response to stimuluscellular component organizationestablishment or maintenance of cell polarityactin filament-based processresponse to stresscell communicationcellular response to stimuluscellular component organizationestablishment or maintenance of cell polarityactin filament-based processresponse to stresscell communicationcellular response to stimuluscellular component organizationestablishment or maintenance of cell polarityactin filament-based processresponse to stresscell communicationcellular response to stimuluscellular component organizationestablishment or maintenance of cell polarityactin filament-based processresponse to stresscell communicationcellular response to stimuluscellular component organizationestablishment or maintenance of cell polarityactin filament-based processresponse to stresscell communicationcellular response to stimuluscellular component organizationestablishment or maintenance of cell polarityactin filament-based processresponse to stresscell communicationcellular response to stimuluscellular component organizationestablishment or maintenance of cell polarityactin filament-based processresponse to stresscell communicationcellular response to stimuluscellular component organizationestablishment or maintenance of cell polarityactin filament-based processresponse to stresscell communicationcellular response to stimuluscellular component orgacellular component organizationestablishment or mainteestablishment or maintenance of cell polarityactin filament-based practin filament-based processresponse to stressresponse to stresscell communicationcell communicationcellular response to stcellular response to stimulus
lipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindinglipid bindingion bindingion bindingprotein bindingprotein binding
cellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenmembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0030950 establishment or maintenance of actin cytoskeleton polarity IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0038203 TORC2 signaling IBA
 biological_processGO:0046580 negative regulation of Ras protein signal transduction IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0031932 TORC2 complex IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0017016 Ras GTPase binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IEA
 molecular_functionGO:0070300 phosphatidic acid binding IEA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
PIP3 activates AKT signaling
CD28 dependent PI3K/Akt signaling
VEGFR2 mediated vascular permeability
Regulation of TP53 Degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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