ENSGALG00000001370


Gallus gallus

Features
Gene ID: ENSGALG00000001370
  
Biological name :ADAMTS8
  
Synonyms : ADAM metallopeptidase with thrombospondin type 1 motif 8 / ADAMTS8
  
Possible biological names infered from orthology : A disintegrin and metalloproteinase with thrombospondin motifs 8 isoform 2 / Q9UP79
  
Species: Gallus gallus
  
Chr. number: 24
Strand: -1
Band:
Gene start: 1657703
Gene end: 1668923
  
Corresponding Affymetrix probe sets: GgaAffx.915.1.S1_at (Chicken Array)   GgaAffx.915.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000002088
Ensembl peptide - ENSGALP00000056933
NCBI entrez gene - 769222     See in Manteia.
RefSeq - XM_015298130
swissprot - A0A1D5PVG5
swissprot - F1NL57
Ensembl - ENSGALG00000001370
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adamts15bENSDARG00000058252Danio rerio
 adamts8aENSDARG00000007709Danio rerio
 Q9UP79ENSG00000134917Homo sapiens
 Adamts8ENSMUSG00000031994Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADAMTS1 / ADAM metallopeptidase with thrombospondin type 1 motif 1 / P97857* / Q9UHI8* / A disintegrin and metalloproteinase with thrombospondin motifs 1 *ENSGALG0000004034250
ADAMTS15 / ADAM metallopeptidase with thrombospondin type 1 motif 15 / P59384* / Q8TE58* / A disintegrin and metalloproteinase with thrombospondin motifs 15 *ENSGALG0000000140746
ADAMTS20 / ADAM metallopeptidase with thrombospondin type 1 motif 20 / P59510* / P59511* / A disintegrin and metalloproteinase with thrombospondin motifs 20 *ENSGALG0000000957240
ADAMTS9 / ADAM metallopeptidase with thrombospondin type 1 motif 9 / Q9P2N4* / a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9*ENSGALG0000004175040
ADAMTS5 / ADAM metallopeptidase with thrombospondin type 1 motif 5 / Q9R001* / Q9UNA0* / A disintegrin and metalloproteinase with thrombospondin motifs 5 *ENSGALG0000001579533
O75173* / Q8BNJ2* / ADAMTS4* / ADAM metallopeptidase with thrombospondin type 1 motif 4* / A disintegrin and metalloproteinase with thrombospondin motifs 4 *ENSGALG0000003050233
ADAMTS13 / ADAM metallopeptidase with thrombospondin type 1 motif 13 / Q769J6* / Q76LX8* / A disintegrin and metalloproteinase with thrombospondin motifs 13 *ENSGALG0000003359722
THSD4 / thrombospondin type 1 domain containing 4 / Q3UTY6* / Q6ZMP0* / Thrombospondin type-1 domain-containing protein 4 *ENSGALG0000000408717
ADAMTSL3 / ADAMTS like 3 / P82987*ENSGALG0000000610416
ADAMTSL2 / ADAMTS like 2 / Q7TSK7* / Q86TH1* / ADAMTS-like protein 2 *ENSGALG0000000295515
PAPLN / papilin, proteoglycan like sulfated glycoprotein / O95428* / Q9EPX2* / Papilin *ENSGALG0000000931515
ENSGALG0000003111915
ENSGALG0000000816413
ENSGALG000000032958
Q8BLI0* / Q8N6G6* / ADAMTSL1* / ADAMTS like 1* / ADAMTS-like protein 1 *ENSGALG000000347608
Q8BLI0* / Q8N6G6* / ADAMTSL1* / ADAMTS like 1* / ADAMTS-like protein 1 *ENSGALG000000205540


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR002870  Peptidase M12B, propeptide
 IPR010294  ADAM-TS Spacer 1
 IPR013277  Peptidase M12B, ADAM-TS8
 IPR024079  Metallopeptidase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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