ENSMUSG00000031994


Mus musculus

Features
Gene ID: ENSMUSG00000031994
  
Biological name :Adamts8
  
Synonyms : Adamts8 / A disintegrin and metalloproteinase with thrombospondin motifs 8 isoform 2
  
Possible biological names infered from orthology : ADAM metallopeptidase with thrombospondin type 1 motif 8 / Q9UP79
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A4
Gene start: 30942562
Gene end: 30963838
  
Corresponding Affymetrix probe sets: 10584047 (MoGene1.0st)   1418270_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000069644
Ensembl peptide - ENSMUSP00000124848
NCBI entrez gene - 30806     See in Manteia.
MGI - MGI:1353468
RefSeq - NM_001326292
RefSeq - NM_013906
RefSeq Peptide - NP_001313221
RefSeq Peptide - NP_038934
swissprot - F8VQ15
swissprot - F6U6K2
Ensembl - ENSMUSG00000031994
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adamts15bENSDARG00000058252Danio rerio
 adamts8aENSDARG00000007709Danio rerio
 ADAMTS8ENSGALG00000001370Gallus gallus
 Q9UP79ENSG00000134917Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P97857 / Adamts1 / A disintegrin and metalloproteinase with thrombospondin motifs 1 / Q9UHI8* / ADAM metallopeptidase with thrombospondin type 1 motif 1*ENSMUSG0000002289347
P59384 / Adamts15 / A disintegrin and metalloproteinase with thrombospondin motifs 15 / Q8TE58* / ADAM metallopeptidase with thrombospondin type 1 motif 15*ENSMUSG0000003345345
Q8BNJ2 / Adamts4 / A disintegrin and metalloproteinase with thrombospondin motifs 4 / O75173* / ADAM metallopeptidase with thrombospondin type 1 motif 4*ENSMUSG0000000640339
P59511 / Adamts20 / A disintegrin and metalloproteinase with thrombospondin motifs 20 / P59510* / ADAM metallopeptidase with thrombospondin type 1 motif 20*ENSMUSG0000002244939
Q9R001 / Adamts5 / A disintegrin and metalloproteinase with thrombospondin motifs 5 / Q9UNA0* / ADAM metallopeptidase with thrombospondin type 1 motif 5*ENSMUSG0000002289439
Q769J6 / Adamts13 / A disintegrin and metalloproteinase with thrombospondin motifs 13 / Q76LX8* / ADAM metallopeptidase with thrombospondin type 1 motif 13*ENSMUSG0000001485221
Adamts9 / a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9 / Q9P2N4* / ADAM metallopeptidase with thrombospondin type 1 motif 9*ENSMUSG0000003002218
Thsd4 / Q3UTY6 / Thrombospondin type-1 domain-containing protein 4 / Q6ZMP0* / thrombospondin type 1 domain containing 4*ENSMUSG0000003228915
Q80T21 / Adamtsl4 / ADAMTS-like protein 4 / Q6UY14* / ADAMTS like 4*ENSMUSG0000001585014
Papln / Q9EPX2 / Papilin / O95428* / papilin, proteoglycan like sulfated glycoprotein*ENSMUSG0000002122314
Q7TSK7 / Adamtsl2 / ADAMTS-like protein 2 / Q86TH1* / ADAMTS like 2*ENSMUSG0000003604014
Adamtsl3 / ADAMTS-like 3 / P82987*ENSMUSG0000007046913
Q8BLI0 / Adamtsl1 / ADAMTS-like protein 1 / Q8N6G6* / ADAMTS like 1*ENSMUSG0000006611312


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR010294  ADAM-TS Spacer 1
 IPR013277  Peptidase M12B, ADAM-TS8
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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