ENSMUSG00000036040


Mus musculus

Features
Gene ID: ENSMUSG00000036040
  
Biological name :Adamtsl2
  
Synonyms : Adamtsl2 / ADAMTS-like protein 2 / Q7TSK7
  
Possible biological names infered from orthology : ADAMTS like 2 / Q86TH1
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: A3
Gene start: 27079379
Gene end: 27108981
  
Corresponding Affymetrix probe sets: 10470392 (MoGene1.0st)   1429214_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000088774
NCBI entrez gene - 77794     See in Manteia.
MGI - MGI:1925044
RefSeq - XM_017319342
RefSeq - NM_029981
RefSeq - XM_006498439
RefSeq Peptide - NP_084257
swissprot - Q7TSK7
swissprot - A1A5B7
Ensembl - ENSMUSG00000036040
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adamtsl2ENSDARG00000074033Danio rerio
 ADAMTSL2ENSGALG00000002955Gallus gallus
 Q86TH1ENSG00000197859Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P59511 / Adamts20 / A disintegrin and metalloproteinase with thrombospondin motifs 20 / P59510* / ADAM metallopeptidase with thrombospondin type 1 motif 20*ENSMUSG0000002244926
Thsd4 / Q3UTY6 / Thrombospondin type-1 domain-containing protein 4 / Q6ZMP0* / thrombospondin type 1 domain containing 4*ENSMUSG0000003228926
Adamts9 / a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9 / Q9P2N4* / ADAM metallopeptidase with thrombospondin type 1 motif 9*ENSMUSG0000003002224
Q80T21 / Adamtsl4 / ADAMTS-like protein 4 / Q6UY14* / ADAMTS like 4*ENSMUSG0000001585023
Adamtsl3 / ADAMTS-like 3 / P82987*ENSMUSG0000007046923
Papln / Q9EPX2 / Papilin / O95428* / papilin, proteoglycan like sulfated glycoprotein*ENSMUSG0000002122322
Q8BLI0 / Adamtsl1 / ADAMTS-like protein 1 / Q8N6G6* / ADAMTS like 1*ENSMUSG0000006611322
Q769J6 / Adamts13 / A disintegrin and metalloproteinase with thrombospondin motifs 13 / Q76LX8* / ADAM metallopeptidase with thrombospondin type 1 motif 13*ENSMUSG0000001485219
P59384 / Adamts15 / A disintegrin and metalloproteinase with thrombospondin motifs 15 / Q8TE58* / ADAM metallopeptidase with thrombospondin type 1 motif 15*ENSMUSG0000003345316
P97857 / Adamts1 / A disintegrin and metalloproteinase with thrombospondin motifs 1 / Q9UHI8* / ADAM metallopeptidase with thrombospondin type 1 motif 1*ENSMUSG0000002289315
Q9R001 / Adamts5 / A disintegrin and metalloproteinase with thrombospondin motifs 5 / Q9UNA0* / ADAM metallopeptidase with thrombospondin type 1 motif 5*ENSMUSG0000002289413
Adamts8 / A disintegrin and metalloproteinase with thrombospondin motifs 8 isoform 2 / Q9UP79* / ADAM metallopeptidase with thrombospondin type 1 motif 8*ENSMUSG0000003199413
Q8BNJ2 / Adamts4 / A disintegrin and metalloproteinase with thrombospondin motifs 4 / O75173* / ADAM metallopeptidase with thrombospondin type 1 motif 4*ENSMUSG0000000640311


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR010294  ADAM-TS Spacer 1
 IPR010909  PLAC
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0030198 extracellular matrix organization IMP
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway ISO
 biological_processGO:0060481 lobar bronchus epithelium development IMP
 cellular_componentGO:0005576 extracellular region IDA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0050436 microfibril binding IPI


Pathways (from Reactome)
Pathway description
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001575 cyanosis "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159]
Show

Allelic Composition: Arid5btm1Whit/Arid5btm1Whit
Genetic Background: B6.129S1-Arid5btm1Whit

 MP:0001943 abnormal respiration "anomaly in the movement of gases into and out of the lung " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Arid5btm1Whit/Arid5btm1Whit
Genetic Background: B6.129S1-Arid5btm1Whit

 MP:0001954 respiratory distress "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
Show

Allelic Composition: Arid5btm1Whit/Arid5btm1Whit
Genetic Background: B6.129S1-Arid5btm1Whit

 MP:0002058 neonatal lethality "death of animal within one day after birth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Arid5btm1Whit/Arid5btm1Whit
Genetic Background: B6.129S1-Arid5btm1Whit

 MP:0010943 abnormal bronchus epithelium morphology "any structural anomaly of the epithelial layer of the bronchi" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Arid5btm1Whit/Arid5btm1Whit
Genetic Background: B6.129S1-Arid5btm1Whit

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr