Manteia

ENSGALG00000001416

Gallus gallus

Features

Gene ID:	ENSGALG00000001416

Biological name :	ADRA1B

Synonyms :	ADRA1B / adrenoceptor alpha 1B

Possible biological names infered from orthology :	P35368

Species:	Gallus gallus

Chr. number:	13
Strand:	-1
Band:
Gene start:	7992487
Gene end:	8008603

Corresponding Affymetrix probe sets:	Gga.3387.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000002155 NCBI entrez gene - 373890 See in Manteia. RefSeq - XM_414483 swissprot - F1NIZ5 Ensembl - ENSGALG00000001416

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
adra1ba	ENSDARG00000011317	Danio rerio
adra1bb	ENSDARG00000041173	Danio rerio
ADRA1B	ENSG00000170214	Homo sapiens
Adra1b	ENSMUSG00000050541	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
ADRA1D* / P25100* / adrenoceptor alpha 1D*	ENSGALG00000038787	52
ADRA1A / adrenoceptor alpha 1A / P35348* / P97718* / Alpha-1A adrenergic receptor *	ENSGALG00000000469	47
HTR1A / 5-hydroxytryptamine receptor 1A / P08908* / Q64264* / 5-hydroxytryptamine (serotonin) receptor 1A*	ENSGALG00000014742	26
HTR7 / 5-hydroxytryptamine receptor 7 / P32304* / P34969* / 5-hydroxytryptamine (serotonin) receptor 7*	ENSGALG00000040549	24
HTR1D / 5-hydroxytryptamine receptor 1D / P28221* / Q61224* / 5-hydroxytryptamine (serotonin) receptor 1D*	ENSGALG00000000820	23
ADRA2C / adrenoceptor alpha 2C / P18825* / Q01337* / Alpha-2C adrenergic receptor *	ENSGALG00000015608	23
HTR1B / 5-hydroxytryptamine receptor 1B / P28222* / P28334* / 5-hydroxytryptamine (serotonin) receptor 1B*	ENSGALG00000015895	23
ADRA2A / adrenoceptor alpha 2A / P08913*	ENSGALG00000023521	23
HTR7L	ENSGALG00000035081	23
HTR1F / 5-hydroxytryptamine receptor 1F / P30939* / Q02284* / 5-hydroxytryptamine (serotonin) receptor 1F*	ENSGALG00000015494	22
HTR1E / 5-hydroxytryptamine receptor 1E / P28566*	ENSGALG00000015826	22
HTR5A / 5-hydroxytryptamine receptor 5A / P30966* / P47898* / 5-hydroxytryptamine (serotonin) receptor 5A*	ENSGALG00000006362	21
	ENSGALG00000035457	20

Protein motifs (from Interpro)

Interpro ID	Name
IPR000276	G protein-coupled receptor, rhodopsin-like
IPR001115	Alpha 1B adrenoceptor
IPR002233	Adrenoceptor family
IPR017452	GPCR, rhodopsin-like, 7TM

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure	IBA
biological_process	GO:0006937	regulation of muscle contraction	IEA
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway	IBA
biological_process	GO:0007204	positive regulation of cytosolic calcium ion concentration	IBA
biological_process	GO:0007267	cell-cell signaling	IBA
biological_process	GO:0019229	regulation of vasoconstriction	IEA
biological_process	GO:0042593	glucose homeostasis	IBA
biological_process	GO:0043410	positive regulation of MAPK cascade	IEA
biological_process	GO:0045907	positive regulation of vasoconstriction	IBA
biological_process	GO:0045987	positive regulation of smooth muscle contraction	IBA
biological_process	GO:0055117	regulation of cardiac muscle contraction	IEA
biological_process	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	IBA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0005887	integral component of plasma membrane	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0031965	nuclear membrane	IEA
molecular_function	GO:0004871	obsolete signal transducer activity	IEA
molecular_function	GO:0004930	G-protein coupled receptor activity	IEA
molecular_function	GO:0004935	adrenergic receptor activity	IEA
molecular_function	GO:0004937	alpha1-adrenergic receptor activity	IBA
molecular_function	GO:0046982	protein heterodimerization activity	IEA

Pathways (from Reactome)

Pathway description

Adrenoceptors

G alpha (q) signalling events

G alpha (12/13) signalling events

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000001334	GNB1 / G protein subunit beta 1 / P62873* / P62874* / guanine nucleotide binding protein (G protein), beta 1*	/ complex / reaction
ENSGALG00000027629	GNG2 / G protein subunit gamma 2 / P59768* / P63213* / guanine nucleotide binding protein (G protein), gamma 2*	/ complex / reaction
ENSGALG00000036028	GNA13 / G protein subunit alpha 13 / P27601* / Q14344* / guanine nucleotide binding protein, alpha 13*	/ complex / reaction

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr