ENSGALG00000015895


Gallus gallus

Features
Gene ID: ENSGALG00000015895
  
Biological name :HTR1B
  
Synonyms : 5-hydroxytryptamine receptor 1B / HTR1B
  
Possible biological names infered from orthology : 5-hydroxytryptamine (serotonin) receptor 1B / P28222 / P28334
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 80361173
Gene end: 80362338
  
Corresponding Affymetrix probe sets: GgaAffx.24802.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000025570
NCBI entrez gene - 421858     See in Manteia.
RefSeq - NM_001172781
RefSeq - XM_015284634
RefSeq Peptide - NP_001166252
swissprot - D3Y1H8
Ensembl - ENSGALG00000015895
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 htr1bENSDARG00000053987Danio rerio
 HTR1BENSG00000135312Homo sapiens
 Htr1bENSMUSG00000049511Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HTR1D / 5-hydroxytryptamine receptor 1D / P28221* / Q61224* / 5-hydroxytryptamine (serotonin) receptor 1D*ENSGALG0000000082063
HTR1E / 5-hydroxytryptamine receptor 1E / P28566*ENSGALG0000001582646
HTR1A / 5-hydroxytryptamine receptor 1A / P08908* / Q64264* / 5-hydroxytryptamine (serotonin) receptor 1A*ENSGALG0000001474243
HTR1F / 5-hydroxytryptamine receptor 1F / P30939* / Q02284* / 5-hydroxytryptamine (serotonin) receptor 1F*ENSGALG0000001549442
HTR7 / 5-hydroxytryptamine receptor 7 / P32304* / P34969* / 5-hydroxytryptamine (serotonin) receptor 7*ENSGALG0000004054934
HTR7LENSGALG0000003508133
HTR5A / 5-hydroxytryptamine receptor 5A / P30966* / P47898* / 5-hydroxytryptamine (serotonin) receptor 5A*ENSGALG0000000636232
ADRA2A / adrenoceptor alpha 2A / P08913*ENSGALG0000002352132
ADRA1B / adrenoceptor alpha 1B / P35368*ENSGALG0000000141631
ADRA2C / adrenoceptor alpha 2C / P18825* / Q01337* / Alpha-2C adrenergic receptor *ENSGALG0000001560831
ADRA1A / adrenoceptor alpha 1A / P35348* / P97718* / Alpha-1A adrenergic receptor *ENSGALG0000000046929
ADRA1D* / P25100* / adrenoceptor alpha 1D*ENSGALG0000003878729
ENSGALG0000003545728


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR002147  5-Hydroxytryptamine 1B receptor
 IPR002231  5-hydroxytryptamine receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002031 G-protein coupled receptor internalization IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway IEA
 biological_processGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0007631 feeding behavior IEA
 biological_processGO:0014063 negative regulation of serotonin secretion IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0042310 vasoconstriction IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0046849 bone remodeling IEA
 biological_processGO:0050795 regulation of behavior IEA
 biological_processGO:0071312 cellular response to alkaloid IEA
 biological_processGO:0071502 cellular response to temperature stimulus IEA
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004993 G-protein coupled serotonin receptor activity IBA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0030594 neurotransmitter receptor activity IBA
 molecular_functionGO:0051378 serotonin binding IEA


Pathways (from Reactome)
Pathway description
Serotonin receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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