ENSGALG00000001946


Gallus gallus

Features
Gene ID: ENSGALG00000001946
  
Biological name :RSPO1
  
Synonyms : RSPO1 / R-spondin-1 precursor
  
Possible biological names infered from orthology : Q2MKA7 / R-spondin 1
  
Species: Gallus gallus
  
Chr. number: 23
Strand: 1
Band:
Gene start: 3731881
Gene end: 3744539
  
Corresponding Affymetrix probe sets: GgaAffx.1288.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000003008
Ensembl peptide - ENSGALP00000059706
NCBI entrez gene - 419613     See in Manteia.
RefSeq - XM_004947756
RefSeq - XM_004947757
RefSeq - XM_417760
RefSeq Peptide - NP_001305373
swissprot - E1BVU3
swissprot - A0A1L1RLR1
Ensembl - ENSGALG00000001946
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rspo1ENSDARG00000104340Danio rerio
 RSPO1ENSG00000169218Homo sapiens
 Rspo1ENSMUSG00000028871Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RSPO3 / Gallus gallus R-spondin 3 (RSPO3), mRNA. / Q2TJ95* / Q9BXY4* / R-spondin 3*ENSGALG0000004260745
RSPO2 / R-spondin-2 precursor / Q8BFU0* / Q6UXX9* / R-spondin 2* / Mus musculus R-spondin 2 (Rspo2), transcript variant 1, mRNA.*ENSGALG0000003003038
RSPO4 / R-spondin 4 / Q2I0M5* / Q8BJ73*ENSGALG0000002364034


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR006212  Furin-like repeat
 IPR009030  Growth factor receptor cysteine-rich domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0002090 regulation of receptor internalization IEA
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 molecular_functionGO:0001664 G-protein coupled receptor binding IEA
 molecular_functionGO:0005102 signaling receptor binding IEA


Pathways (from Reactome)
Pathway description
Regulation of FZD by ubiquitination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001028 RNF43 / ring finger protein 43 / Q5NCP0* / Q68DV7* / E3 ubiquitin-protein ligase RNF43 *  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction
 ENSGALG00000010163 LGR5 / leucine rich repeat containing G protein-coupled receptor 5 / O75473* / Q9Z1P4*  / complex / reaction
 ENSGALG00000040834 LGR4 / leucine rich repeat containing G protein-coupled receptor 4 / A2ARI4* / Q9BXB1*  / complex / reaction






 

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