ENSGALG00000042607


Gallus gallus
regulationsignalingbindingRSPO3repeatreceptorangiogenesiswntpathwaythrombospondintype-tspfurin-likegrowthfactorcysteine-richdomainsuperfamilybloodvesselremodelingsproutingbranchinginvolvedlabyrinthinelayermorphogenesiscanonicalnon-canonicalextracellularregion

Features
Gene ID: ENSGALG00000042607
  
Biological name :RSPO3
  
Synonyms : Gallus gallus R-spondin 3 (RSPO3), mRNA. / RSPO3
  
Possible biological names infered from orthology : Q2TJ95 / Q9BXY4 / R-spondin 3
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 59438707
Gene end: 59496891
  
Corresponding Affymetrix probe sets: Gga.1605.1.S1_s_at (Chicken Array)   Gga.1605.2.S1_at (Chicken Array)   Gga.19305.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048902
NCBI entrez gene - 421715     See in Manteia.
RefSeq - NM_001319025
RefSeq - XM_419752
RefSeq Peptide - NP_001305954
swissprot - A0A1D5P857
Ensembl - ENSGALG00000042607
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rspo3ENSDARG00000070081Danio rerio
 RSPO3ENSG00000146374Homo sapiens
 Rspo3ENSMUSG00000019880Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RSPO1 / R-spondin-1 precursor / Q2MKA7* / R-spondin 1*ENSGALG0000000194642
RSPO2 / R-spondin-2 precursor / Q8BFU0* / Q6UXX9* / R-spondin 2* / Mus musculus R-spondin 2 (Rspo2), transcript variant 1, mRNA.*ENSGALG0000003003037
RSPO4 / R-spondin 4 / Q2I0M5* / Q8BJ73*ENSGALG0000002364031


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR006212  Furin-like repeat
 IPR009030  Growth factor receptor cysteine-rich domain superfamily


Gene Ontology (GO)
anatomical structure developmenttissue remodelingcell communicationcellular response to stimulusanatomical structure developmenttissue remodelingcell communicationcellular response to stimulusanatomical structure developmenttissue remodelingcell communicationcellular response to stimulusanatomical structure developmenttissue remodelingcell communicationcellular response to stimulusanatomical structure developmenttissue remodelingcell communicationcellular response to stimulusanatomical structure developmenttissue remodelingcell communicationcellular response to stimulusanatomical structure developmenttissue remodelingcell communicationcellular response to stimulusanatomical structure developmenttissue remodelingcell communicationcellular response to stimulusanatomical structure developmenttissue remodelingcell communicationcellular response to stimulusanatomical structure developmenttissue remodelingcell communicationcellular response to stimulusanatomical structure developmentanatomical structure developmenttissue remodelingtissue remodelingcell communicationcell communicationcellular response to stimuluscellular response to stimulus
protein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingprotein bindingprotein bindingion bindingion bindingcarbohydrate derivative bindingcarbohydrate derivative bindingsulfur compound bindingsulfur compound binding
extracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001974 blood vessel remodeling IEA
 biological_processGO:0002040 sprouting angiogenesis IEA
 biological_processGO:0060670 branching involved in labyrinthine layer morphogenesis IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:2000052 positive regulation of non-canonical Wnt signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IEA
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
Regulation of FZD by ubiquitination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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