ENSGALG00000002594


Gallus gallus

Features
Gene ID: ENSGALG00000002594
  
Biological name :TFPI
  
Synonyms : TFPI / tissue factor pathway inhibitor
  
Possible biological names infered from orthology : O54819 / P10646
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 1055959
Gene end: 1083282
  
Corresponding Affymetrix probe sets: Gga.11741.1.S1_a_at (Chicken Array)   Gga.11741.3.S1_a_at (Chicken Array)   Gga.11741.4.A1_at (Chicken Array)   Gga.11741.4.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000033380
Ensembl peptide - ENSGALP00000057798
NCBI entrez gene - 423989     See in Manteia.
RefSeq - XM_004942401
RefSeq - XM_004942402
RefSeq - XM_004942403
RefSeq - XM_004942404
RefSeq - XM_004942405
RefSeq - XM_004942406
RefSeq - XM_004942407
RefSeq - XM_015289184
RefSeq - XM_015289185
RefSeq - XM_015289186
RefSeq - XM_015289187
RefSeq - XM_015289188
RefSeq - XM_015289189
RefSeq - XM_015289190
RefSeq - XM_015289191
RefSeq - XM_015289192
RefSeq - XM_015289193
RefSeq - XM_015289194
RefSeq - XM_015289195
RefSeq - XM_015289196
RefSeq - XM_015289197
RefSeq - XM_015289198
RefSeq - XM_015289199
RefSeq - XM_015289200
RefSeq - XM_015289201
RefSeq - XM_421849
RefSeq - XM_001232100
RefSeq - XM_004942400
swissprot - E1BUM2
Ensembl - ENSGALG00000002594
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tfpiaENSDARG00000034718Danio rerio
 TFPIENSG00000003436Homo sapiens
 TfpiENSMUSG00000027082Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TFPI2 / tissue factor pathway inhibitor 2 / O35536* / P48307*ENSGALG0000000951226
WFIKKN2 / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 / Q7TQN3* / Q8TEU8*ENSGALG0000000736718
WFIKKN1 / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 / Q8R0S6* / Q96NZ8* / WAP, FS, Ig, KU, and NTR-containing protein 1*ENSGALG0000000004417
SPINT1 / serine peptidase inhibitor, Kunitz type 1 / O43278* / Q9R097* / Kunitz-type protease inhibitor 1 *ENSGALG0000000846917
AMBP / protein AMBP precursor / P02760* / Q07456* / alpha-1-microglobulin/bikunin precursor* / Protein AMBP Alpha-1-microglobulin Inter-alpha-trypsin inhibitor light chain Trypstatin*ENSGALG0000003025515


Protein motifs (from Interpro)
Interpro ID Name
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site
 IPR029864  Tissue factor pathway inhibitor 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0030195 negative regulation of blood coagulation IEA
 biological_processGO:0071383 cellular response to steroid hormone stimulus IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005901 caveola IEA
 cellular_componentGO:0009986 cell surface IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Extrinsic Pathway of Fibrin Clot Formation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000005619 F3* / P13726* / coagulation factor III, tissue factor*  / complex / reaction
 ENSGALG00000016833 F7 / coagulation factor VII precursor / P08709* / P70375* / coagulation factor VII* / Coagulation factor VII Factor VII light chain Factor VII heavy chain*  / complex / reaction
 ENSGALG00000026677 F10 / P25155 / Coagulation factor X Factor X light chain Factor X heavy chain Activated factor Xa heavy chain / O88947* / P00742* / coagulation factor X*  / complex / reaction






 

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