ENSGALG00000002960


Gallus gallus

Features
Gene ID: ENSGALG00000002960
  
Biological name :HMGCS2
  
Synonyms : 3-hydroxy-3-methylglutaryl-CoA synthase 2 / HMGCS2
  
Possible biological names infered from orthology : Hydroxymethylglutaryl-CoA synthase, mitochondrial / P54868 / P54869
  
Species: Gallus gallus
  
Chr. number: 8
Strand: 1
Band:
Gene start: 4260456
Gene end: 4264048
  
Corresponding Affymetrix probe sets: Gga.2523.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004672
NCBI entrez gene - 424380     See in Manteia.
RefSeq - XM_422225
swissprot - E1C9C4
Ensembl - ENSGALG00000002960
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HMGCS2ENSG00000134240Homo sapiens
 Hmgcs2ENSMUSG00000027875Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HMGCS1 / hydroxymethylglutaryl-CoA synthase, cytoplasmic / Q01581* / Q8JZK9* / 3-hydroxy-3-methylglutaryl-CoA synthase 1*ENSGALG0000001486267


Protein motifs (from Interpro)
Interpro ID Name
 IPR000590  Hydroxymethylglutaryl-coenzyme A synthase, active site
 IPR010122  Hydroxymethylglutaryl-CoA synthase, eukaryotic
 IPR013528  Hydroxymethylglutaryl-coenzyme A synthase, N-terminal
 IPR013746  Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain
 IPR016039  Thiolase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008202 steroid metabolic process IEA
 biological_processGO:0008299 isoprenoid biosynthetic process IEA
 biological_processGO:0016126 sterol biosynthetic process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004421 hydroxymethylglutaryl-CoA synthase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of Ketone Bodies


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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