Manteia

ENSGALG00000003021

Gallus gallus

Features

Gene ID:	ENSGALG00000003021

Biological name :	CHRNA5

Synonyms :	CHRNA5 / neuronal acetylcholine receptor subunit alpha-5 precursor

Possible biological names infered from orthology :	cholinergic receptor nicotinic alpha 5 subunit / cholinergic receptor, nicotinic, alpha polypeptide 5 / P30532 / Q2MKA5

Species:	Gallus gallus

Chr. number:	10
Strand:	-1
Band:
Gene start:	3569395
Gene end:	3580686

Corresponding Affymetrix probe sets:	Gga.5094.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000058178 Ensembl peptide - ENSGALP00000004767 NCBI entrez gene - 386577 See in Manteia. RefSeq - NM_204415 RefSeq Peptide - NP_989746 swissprot - F1NAI4 swissprot - A0A1D5PYX0 Ensembl - ENSGALG00000003021

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
chrna5	ENSDARG00000003420	Danio rerio
CHRNA5	ENSG00000169684	Homo sapiens
Chrna5	ENSMUSG00000035594	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
CHRNB3 / cholinergic receptor nicotinic beta 3 subunit / Q05901* / Q8BMN3* / cholinergic receptor, nicotinic, beta polypeptide 3*	ENSGALG00000015384	65
CHRNA4 / neuronal acetylcholine receptor subunit alpha-4 precursor / O70174* / P43681* / cholinergic receptor nicotinic alpha 4 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 4*	ENSGALG00000005801	52
CHRNA2 / neuronal acetylcholine receptor subunit alpha-2 precursor / Q15822* / Q91X60* / cholinergic receptor nicotinic alpha 2 subunit* / cholinergic receptor, nicotinic, alpha polypeptid...	ENSGALG00000016565	52
CHRNA3 / P09481 / Neuronal acetylcholine receptor subunit alpha-3 / P32297* / cholinergic receptor nicotinic alpha 3 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 3*	ENSGALG00000003014	48
CHRNA6 / neuronal acetylcholine receptor subunit alpha-6 precursor / Q15825* / Q9R0W9* / cholinergic receptor nicotinic alpha 6 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 6*	ENSGALG00000015382	48
CHRNA1 / acetylcholine receptor subunit alpha precursor / P02708* / P04756* / cholinergic receptor nicotinic alpha 1 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)*	ENSGALG00000009301	43
CHRNB2 / neuronal acetylcholine receptor subunit beta-2 precursor / P17787* / Q9ERK7* / cholinergic receptor nicotinic beta 2 subunit* / cholinergic receptor, nicotinic, beta polypeptide 2...	ENSGALG00000002707	41
CHRNB4 / neuronal acetylcholine receptor subunit beta-4 precursor / P30926* / Q8R493* / cholinergic receptor nicotinic beta 4 subunit* / cholinergic receptor, nicotinic, beta polypeptide 4*	ENSGALG00000003005	41

Protein motifs (from Interpro)

Interpro ID	Name
IPR002394	Nicotinic acetylcholine receptor
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain
IPR006201	Neurotransmitter-gated ion-channel
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain
IPR018000	Neurotransmitter-gated ion-channel, conserved site

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006811	ion transport	IEA
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0034220	ion transmembrane transport	IEA
biological_process	GO:0035094	response to nicotine	IEA
biological_process	GO:0035095	behavioral response to nicotine	IEA
biological_process	GO:0060078	regulation of postsynaptic membrane potential	IEA
biological_process	GO:0060079	excitatory postsynaptic potential	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0005892	acetylcholine-gated channel complex	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0030054	cell junction	IEA
cellular_component	GO:0045202	synapse	IEA
cellular_component	GO:0045211	postsynaptic membrane	IEA
molecular_function	GO:0004888	transmembrane signaling receptor activity	IEA
molecular_function	GO:0005216	ion channel activity	IEA
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity	IEA
molecular_function	GO:0015464	acetylcholine receptor activity	IEA
molecular_function	GO:0022848	acetylcholine-gated cation-selective channel activity	IEA

Pathways (from Reactome)

Pathway description

Highly calcium permeable postsynaptic nicotinic acetylcholine receptors

Highly calcium permeable nicotinic acetylcholine receptors

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr