Manteia

ENSGALG00000009301

Gallus gallus

Features

Gene ID:	ENSGALG00000009301

Biological name :	CHRNA1

Synonyms :	acetylcholine receptor subunit alpha precursor / CHRNA1

Possible biological names infered from orthology :	cholinergic receptor nicotinic alpha 1 subunit / cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) / P02708 / P04756

Species:	Gallus gallus

Chr. number:	7
Strand:	1
Band:
Gene start:	16865856
Gene end:	16875595

Corresponding Affymetrix probe sets:	Gga.4134.1.S1_at (Chicken Array) Gga.4134.1.S2_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000015122 Ensembl peptide - ENSGALP00000050914 Ensembl peptide - ENSGALP00000046874 NCBI entrez gene - 395608 See in Manteia. RefSeq - NM_204816 RefSeq - XM_015289380 RefSeq Peptide - NP_990147 swissprot - E1BT92 swissprot - A0A1D5PDR8 swissprot - A0A1D5P2H9 Ensembl - ENSGALG00000009301

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
chrna1	ENSDARG00000009021	Danio rerio
CHRNA1	ENSG00000138435	Homo sapiens
Chrna1	ENSMUSG00000027107	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
CHRNA3 / P09481 / Neuronal acetylcholine receptor subunit alpha-3 / P32297* / cholinergic receptor nicotinic alpha 3 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 3*	ENSGALG00000003014	45
CHRNA4 / neuronal acetylcholine receptor subunit alpha-4 precursor / O70174* / P43681* / cholinergic receptor nicotinic alpha 4 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 4*	ENSGALG00000005801	45
CHRNA2 / neuronal acetylcholine receptor subunit alpha-2 precursor / Q15822* / Q91X60* / cholinergic receptor nicotinic alpha 2 subunit* / cholinergic receptor, nicotinic, alpha polypeptid...	ENSGALG00000016565	45
CHRNA6 / neuronal acetylcholine receptor subunit alpha-6 precursor / Q15825* / Q9R0W9* / cholinergic receptor nicotinic alpha 6 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 6*	ENSGALG00000015382	42
CHRNA5 / neuronal acetylcholine receptor subunit alpha-5 precursor / P30532* / Q2MKA5* / cholinergic receptor nicotinic alpha 5 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 5*	ENSGALG00000003021	41
CHRNB2 / neuronal acetylcholine receptor subunit beta-2 precursor / P17787* / Q9ERK7* / cholinergic receptor nicotinic beta 2 subunit* / cholinergic receptor, nicotinic, beta polypeptide 2...	ENSGALG00000002707	40
CHRNB4 / neuronal acetylcholine receptor subunit beta-4 precursor / P30926* / Q8R493* / cholinergic receptor nicotinic beta 4 subunit* / cholinergic receptor, nicotinic, beta polypeptide 4*	ENSGALG00000003005	40
CHRNB3 / cholinergic receptor nicotinic beta 3 subunit / Q05901* / Q8BMN3* / cholinergic receptor, nicotinic, beta polypeptide 3*	ENSGALG00000015384	38

Protein motifs (from Interpro)

Interpro ID	Name
IPR002394	Nicotinic acetylcholine receptor
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain
IPR006201	Neurotransmitter-gated ion-channel
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain
IPR018000	Neurotransmitter-gated ion-channel, conserved site

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0003009	skeletal muscle contraction	IEA
biological_process	GO:0006811	ion transport	IEA
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007274	neuromuscular synaptic transmission	IEA
biological_process	GO:0007528	neuromuscular junction development	IEA
biological_process	GO:0019228	neuronal action potential	IEA
biological_process	GO:0034220	ion transmembrane transport	IEA
biological_process	GO:0042391	regulation of membrane potential	IEA
biological_process	GO:0046716	muscle cell cellular homeostasis	IEA
biological_process	GO:0048630	skeletal muscle tissue growth	IEA
biological_process	GO:0050881	musculoskeletal movement	IEA
biological_process	GO:0050905	neuromuscular process	IEA
biological_process	GO:0060078	regulation of postsynaptic membrane potential	IEA
biological_process	GO:0060079	excitatory postsynaptic potential	IEA
biological_process	GO:0070050	neuron cellular homeostasis	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0005892	acetylcholine-gated channel complex	IEA
cellular_component	GO:0009986	cell surface	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0030054	cell junction	IEA
cellular_component	GO:0031594	neuromuscular junction	IEA
cellular_component	GO:0045202	synapse	IEA
cellular_component	GO:0045211	postsynaptic membrane	IEA
molecular_function	GO:0004888	transmembrane signaling receptor activity	IEA
molecular_function	GO:0005216	ion channel activity	IEA
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity	IEA
molecular_function	GO:0015464	acetylcholine receptor activity	IEA
molecular_function	GO:0022848	acetylcholine-gated cation-selective channel activity	IEA
molecular_function	GO:0042166	acetylcholine binding	IEA

Pathways (from Reactome)

Pathway description

Highly calcium permeable postsynaptic nicotinic acetylcholine receptors

Highly calcium permeable nicotinic acetylcholine receptors

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr