ENSGALG00000003131


Gallus gallus
kinaseDGKEdiacylglyceroldomainactivityproteinnadsignaltransductionphosphorylationmembranebindingaccessorycatalyticc-likephorbolesterdiacylglycerol-bindingkinase-likesuperfamilyc-activatingg-proteincoupledreceptorsignalingpathwaymetabolicprocessintracellularlipidnucleus

Features
Gene ID: ENSGALG00000003131
  
Biological name :DGKE
  
Synonyms : DGKE / diacylglycerol kinase epsilon
  
Possible biological names infered from orthology : P52429 / Q9R1C6
  
Species: Gallus gallus
  
Chr. number: 18
Strand: 1
Band:
Gene start: 6337106
Gene end: 6344590
  
Corresponding Affymetrix probe sets: Gga.6408.1.S1_at (Chicken Array)   GgaAffx.25759.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004941
NCBI entrez gene - 770911     See in Manteia.
RefSeq - XM_001234225
swissprot - E1C3R5
Ensembl - ENSGALG00000003131
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dgkeENSDARG00000104793Danio rerio
 DGKEENSG00000153933Homo sapiens
 DgkeENSMUSG00000000276Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DGKB / diacylglycerol kinase beta / Q6NS52* / Q9Y6T7*ENSGALG0000003356135
ENSGALG0000000384134
DGKG / diacylglycerol kinase gamma / P49619* / Q91WG7*ENSGALG0000000572134
DGKD / diacylglycerol kinase delta / Q16760*ENSGALG0000000173033
DGKQ / diacylglycerol kinase theta / P52824* / Q6P5E8*ENSGALG0000000214233
DGKH / diacylglycerol kinase eta / Q86XP1*ENSGALG0000001695933
DGKA / diacylglycerol kinase alpha / O88673* / P23743* / Mus musculus diacylglycerol kinase, alpha (Dgka), transcript variant 2, mRNA.*ENSGALG0000003811033
DGKI / diacylglycerol kinase iota / O75912* / diacylglycerol kinase iota isoform 2 *ENSGALG0000001289030
DGKZ / diacylglycerol kinase zeta / Q13574* / Q80UP3*ENSGALG0000000838029


Protein motifs (from Interpro)
Interpro ID Name
 IPR000756  Diacylglycerol kinase, accessory domain
 IPR001206  Diacylglycerol kinase, catalytic domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR016064  NAD kinase/diacylglycerol kinase-like domain superfamily


Gene Ontology (GO)
cell communicationcellular response to stimuluscellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcell communicationcellular response to stimulucellular response to stimuluscellular metabolic processcellular metabolic processprimary metabolic processprimary metabolic processorganic substance metabolic organic substance metabolic process
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compoorganic cyclic compound bindingheterocyclic compounheterocyclic compound bindingsmall molecule bindismall molecule bindingtransferase activitytransferase activityion bindingion bindingcarbohydrate derivatcarbohydrate derivative bindingdrug bindingdrug binding
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0046834 lipid phosphorylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003951 NAD+ kinase activity IEA
 molecular_functionGO:0004143 diacylglycerol kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Effects of PIP2 hydrolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr