ENSGALG00000012890


Gallus gallus

Features
Gene ID: ENSGALG00000012890
  
Biological name :DGKI
  
Synonyms : DGKI / diacylglycerol kinase iota
  
Possible biological names infered from orthology : diacylglycerol kinase iota isoform 2 / O75912
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 57491613
Gene end: 57698081
  
Corresponding Affymetrix probe sets: Gga.18993.1.S1_at (Chicken Array)   GgaAffx.24033.1.S1_at (Chicken Array)   GgaAffx.24033.1.S1_s_at (Chicken Array)   GgaAffx.24033.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000020990
NCBI entrez gene - 418124     See in Manteia.
RefSeq - XM_015286157
swissprot - F1P1H5
Ensembl - ENSGALG00000012890
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01020835.1ENSDARG00000063578Danio rerio
 DGKIENSG00000157680Homo sapiens
 DgkiENSMUSG00000038665Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DGKZ / diacylglycerol kinase zeta / Q13574* / Q80UP3*ENSGALG0000000838062
DGKD / diacylglycerol kinase delta / Q16760*ENSGALG0000000173022
ENSGALG0000000384122
DGKH / diacylglycerol kinase eta / Q86XP1*ENSGALG0000001695922
DGKB / diacylglycerol kinase beta / Q6NS52* / Q9Y6T7*ENSGALG0000003356120
DGKA / diacylglycerol kinase alpha / O88673* / P23743* / Mus musculus diacylglycerol kinase, alpha (Dgka), transcript variant 2, mRNA.*ENSGALG0000003811020
DGKG / diacylglycerol kinase gamma / P49619* / Q91WG7*ENSGALG0000000572119
DGKQ / diacylglycerol kinase theta / P52824* / Q6P5E8*ENSGALG0000000214218
DGKE / diacylglycerol kinase epsilon / P52429* / Q9R1C6*ENSGALG0000000313117


Protein motifs (from Interpro)
Interpro ID Name
 IPR000756  Diacylglycerol kinase, accessory domain
 IPR001206  Diacylglycerol kinase, catalytic domain
 IPR002110  Ankyrin repeat
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR016064  NAD kinase/diacylglycerol kinase-like domain superfamily
 IPR020683  Ankyrin repeat-containing domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007269 neurotransmitter secretion IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0034260 negative regulation of GTPase activity IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0046579 positive regulation of Ras protein signal transduction IEA
 biological_processGO:0046834 lipid phosphorylation IEA
 biological_processGO:0046959 habituation IEA
 biological_processGO:0051966 regulation of synaptic transmission, glutamatergic IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:1900452 regulation of long term synaptic depression IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0032045 guanyl-nucleotide exchange factor complex IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003951 NAD+ kinase activity IEA
 molecular_functionGO:0004143 diacylglycerol kinase activity IEA
 molecular_functionGO:0005095 GTPase inhibitor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017016 Ras GTPase binding IEA


Pathways (from Reactome)
Pathway description
Effects of PIP2 hydrolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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