ENSGALG00000003199


Gallus gallus

Features
Gene ID: ENSGALG00000003199
  
Biological name :MLX
  
Synonyms : MLX / MLX, MAX dimerization protein
  
Possible biological names infered from orthology : MAX-like protein X / Q9UH92
  
Species: Gallus gallus
  
Chr. number: 27
Strand: 1
Band:
Gene start: 5390278
Gene end: 5394159
  
Corresponding Affymetrix probe sets: Gga.4693.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005059
NCBI entrez gene - 420026     See in Manteia.
RefSeq - NM_001030930
RefSeq Peptide - NP_001026101
swissprot - Q5ZKP9
Ensembl - ENSGALG00000003199
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mlxENSDARG00000037891Danio rerio
 MLXENSG00000108788Homo sapiens
 MlxENSMUSG00000017801Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MLXIP / MLX interacting protein / Q9HAP2*ENSGALG0000000439726
MLXIPL / carbohydrate-responsive element-binding protein / Q99MZ3* / Q9NP71* / MLX interacting protein like*ENSGALG0000003496022


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR032647  Max-like protein X


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
ChREBP activates metabolic gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000034960 MLXIPL / carbohydrate-responsive element-binding protein / Q99MZ3* / Q9NP71* / MLX interacting protein like*  / complex






 

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