ENSGALG00000034960


Gallus gallus

Features
Gene ID: ENSGALG00000034960
  
Biological name :MLXIPL
  
Synonyms : carbohydrate-responsive element-binding protein / MLXIPL
  
Possible biological names infered from orthology : MLX interacting protein like / Q99MZ3 / Q9NP71
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 169275
Gene end: 184322
  
Corresponding Affymetrix probe sets: GgaAffx.449.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047840
Ensembl peptide - ENSGALP00000062577
Ensembl peptide - ENSGALP00000052293
Ensembl peptide - ENSGALP00000048395
NCBI entrez gene - 101751014     See in Manteia.
RefSeq - XM_015295648
RefSeq - XM_015295653
RefSeq - XM_015295652
RefSeq - XM_015295650
RefSeq - NM_001110841
RefSeq - XM_015295649
RefSeq Peptide - NP_001104311
swissprot - A0A1L1RUS8
swissprot - A0A1D5P575
swissprot - A0A1D5P6R5
swissprot - A0A1D5PHL3
Ensembl - ENSGALG00000034960
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mlxiplENSDARG00000089107Danio rerio
 MLXIPLENSG00000009950Homo sapiens
 MlxiplENSMUSG00000005373Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MLXIP / MLX interacting protein / Q9HAP2*ENSGALG0000000439729
MLX / MLX, MAX dimerization protein / Q9UH92* / MAX-like protein X*ENSGALG000000031996


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010255 glucose mediated signaling pathway IEA
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0045723 positive regulation of fatty acid biosynthetic process IEA
 biological_processGO:0045821 positive regulation of glycolytic process IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046889 positive regulation of lipid biosynthetic process IEA
 biological_processGO:0071157 negative regulation of cell cycle arrest IEA
 biological_processGO:0090324 negative regulation of oxidative phosphorylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
PKA-mediated phosphorylation of key metabolic factors
ChREBP activates metabolic gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003199 MLX / MLX, MAX dimerization protein / Q9UH92* / MAX-like protein X*  / complex






 

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