ENSGALG00000003572


Gallus gallus

Features
Gene ID: ENSGALG00000003572
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : AC008878.3 / ARHGEF18 / Q6P9R4 / Q6ZSZ5 / Rho guanine nucleotide exchange factor 18 / Rho/Rac guanine nucleotide exchange factor 18
  
Species: Gallus gallus
  
Chr. number: 28
Strand: -1
Band:
Gene start: 4085166
Gene end: 4125847
  
Corresponding Affymetrix probe sets: Gga.7773.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050286
Ensembl peptide - ENSGALP00000005645
NCBI entrez gene - 420132     See in Manteia.
RefSeq - XM_418249
RefSeq - XM_015300164
RefSeq - XM_015300165
RefSeq - XM_015300162
RefSeq - XM_015300163
swissprot - F1NJU1
swissprot - A0A1D5PC02
Ensembl - ENSGALG00000003572
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgef18aENSDARG00000011157Danio rerio
 arhgef18bENSDARG00000042308Danio rerio
 AC008878.3ENSG00000268861Homo sapiens
 Q6ZSZ5ENSG00000104880Homo sapiens
 Q6P9R4ENSMUSG00000004568Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARHGEF28 / Rho guanine nucleotide exchange factor 28 / Q8N1W1*ENSGALG0000001492326
AKAP13 / A-kinase anchoring protein 13 / E9Q394* / Q12802* / A-kinase anchor protein 13 *ENSGALG0000000684023
ARHGEF12 / Rho guanine nucleotide exchange factor 12 / Q8R4H2* / Q9NZN5* / Mus musculus Rho guanine nucleotide exchange factor (GEF) 12 (Arhgef12), transcript variant 2, mRNA.*ENSGALG0000000666311
ARHGEF11 / Rho guanine nucleotide exchange factor 11 / O15085* / Rho guanine nucleotide exchange factor (GEF) 11*ENSGALG0000003916310
ARHGEF3 / rho guanine nucleotide exchange factor 3 / Q91X46* / Q9NR81*ENSGALG000000054816
NET1 / neuroepithelial cell transforming 1 / Q7Z628* / Q9Z206* / neuroepithelial cell transforming gene 1*ENSGALG000000084375
ENSGALG000000264605


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001849  Pleckstrin homology domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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