ENSGALG00000039163


Gallus gallus

Features
Gene ID: ENSGALG00000039163
  
Biological name :ARHGEF11
  
Synonyms : ARHGEF11 / Rho guanine nucleotide exchange factor 11
  
Possible biological names infered from orthology : O15085 / Rho guanine nucleotide exchange factor (GEF) 11
  
Species: Gallus gallus
  
Chr. number: 25
Strand: 1
Band:
Gene start: 1357719
Gene end: 1378793
  
Corresponding Affymetrix probe sets: GgaAffx.8440.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044672
Ensembl peptide - ENSGALP00000058373
Ensembl peptide - ENSGALP00000054507
Ensembl peptide - ENSGALP00000049384
Ensembl peptide - ENSGALP00000046273
NCBI entrez gene - 425979     See in Manteia.
RefSeq - XM_015298456
RefSeq - XM_015298451
RefSeq - XM_015298452
RefSeq - XM_015298453
RefSeq - XM_015298454
RefSeq - XM_015298455
RefSeq - XM_015298444
RefSeq - XM_015298445
RefSeq - XM_015298446
RefSeq - XM_015298447
RefSeq - XM_015298448
RefSeq - XM_015298449
RefSeq - XM_015298450
swissprot - A0A1D5PZG0
swissprot - A0A1D5PNR3
swissprot - A0A1D5P9I0
swissprot - A0A1D5P0U4
swissprot - A0A1D5NWD3
Ensembl - ENSGALG00000039163
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgef11ENSDARG00000052482Danio rerio
 O15085ENSG00000132694Homo sapiens
 Arhgef11ENSMUSG00000041977Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARHGEF12 / Rho guanine nucleotide exchange factor 12 / Q8R4H2* / Q9NZN5* / Mus musculus Rho guanine nucleotide exchange factor (GEF) 12 (Arhgef12), transcript variant 2, mRNA.*ENSGALG0000000666325
ARHGEF28 / Rho guanine nucleotide exchange factor 28 / Q8N1W1*ENSGALG0000001492312
Q6P9R4* / Q6ZSZ5* / ARHGEF18* / AC008878.3* / Rho guanine nucleotide exchange factor 18 * / Rho/Rac guanine nucleotide exchange factor 18*ENSGALG000000035729
AKAP13 / A-kinase anchoring protein 13 / E9Q394* / Q12802* / A-kinase anchor protein 13 *ENSGALG000000068408
NET1 / neuroepithelial cell transforming 1 / Q7Z628* / Q9Z206* / neuroepithelial cell transforming gene 1*ENSGALG000000084376
ARHGEF3 / rho guanine nucleotide exchange factor 3 / Q91X46* / Q9NR81*ENSGALG000000054815
ENSGALG000000264605


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001331  Guanine-nucleotide dissociation stimulator, CDC24, conserved site
 IPR001478  PDZ domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR015212  Regulator of G protein signalling-like domain
 IPR016137  RGS domain
 IPR032919  Rho guanine nucleotide exchange factor 11


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007266 Rho protein signal transduction IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0001664 G-protein coupled receptor binding IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events
Sema4D induced cell migration and growth-cone collapse


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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