ENSGALG00000003948


Gallus gallus

Features
Gene ID: ENSGALG00000003948
  
Biological name :ALAS1
  
Synonyms : 5-aminolevulinate synthase, nonspecific, mitochondrial precursor / ALAS1
  
Possible biological names infered from orthology : 5-aminolevulinate synthase 1 / 5-aminolevulinate synthase, nonspecific, mitochondrial / P13196 / Q8VC19
  
Species: Gallus gallus
  
Chr. number: 12
Strand: 1
Band:
Gene start: 2927404
Gene end: 2936421
  
Corresponding Affymetrix probe sets: Gga.1399.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000035503
Ensembl peptide - ENSGALP00000062508
Ensembl peptide - ENSGALP00000060640
Ensembl peptide - ENSGALP00000058614
Ensembl peptide - ENSGALP00000054575
Ensembl peptide - ENSGALP00000046192
NCBI entrez gene - 552895     See in Manteia.
RefSeq - NM_001018012
RefSeq Peptide - NP_001018012
swissprot - A0A1L1RPD8
swissprot - A0A1L1RIP4
swissprot - E1C5T4
swissprot - A0A1D5P0L4
swissprot - A0A1D5PNX9
swissprot - A0A1L1RUK5
Ensembl - ENSGALG00000003948
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 alas1ENSDARG00000021059Danio rerio
 ALAS1ENSG00000023330Homo sapiens
 Alas1ENSMUSG00000032786Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GCAT / glycine C-acetyltransferase / O75600* / O88986* / 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial *ENSGALG0000001231219


Protein motifs (from Interpro)
Interpro ID Name
 IPR001917  Aminotransferase, class-II, pyridoxal-phosphate binding site
 IPR004839  Aminotransferase, class I/classII
 IPR010961  Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase
 IPR015118  5-aminolevulinate synthase presequence
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006778 porphyrin-containing compound metabolic process IEA
 biological_processGO:0006782 protoporphyrinogen IX biosynthetic process IEA
 biological_processGO:0006783 heme biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0033014 tetrapyrrole biosynthetic process IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003870 5-aminolevulinate synthase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Heme biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr