ENSGALG00000004096


Gallus gallus

Features
Gene ID: ENSGALG00000004096
  
Biological name :CHRNA7
  
Synonyms : CHRNA7
  
Possible biological names infered from orthology : cholinergic receptor nicotinic alpha 7 subunit / cholinergic receptor, nicotinic, alpha polypeptide 7 / CHRFAM7A / CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion / P36544 / P49582 / Q494W8
  
Species: Gallus gallus
  
Chr. number: 10
Strand: -1
Band:
Gene start: 6597145
Gene end: 6637179
  
Corresponding Affymetrix probe sets: Gga.16410.1.S1_at (Chicken Array)   Gga.4000.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000006509
NCBI entrez gene - 374001     See in Manteia.
RefSeq - NM_204181
RefSeq Peptide - NP_989512
swissprot - F1P4Y5
Ensembl - ENSGALG00000004096
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chrna7ENSDARG00000101702Danio rerio
 FO907089.1ENSDARG00000101522Danio rerio
 CHRNA7ENSG00000175344Homo sapiens
 Q494W8ENSG00000166664Homo sapiens
 Chrna7ENSMUSG00000030525Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHRNA7LENSGALG0000001533669
CHRNA10 / neuronal acetylcholine receptor subunit alpha-10 precursor ENSGALG0000002270235
CHRNA9 / Q9PTS8 / Neuronal acetylcholine receptor subunit alpha-9 / Q9UGM1* / cholinergic receptor nicotinic alpha 9 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 9*ENSGALG0000001426833
CHRND / acetylcholine receptor subunit delta precursor / P02716* / Q07001* / cholinergic receptor nicotinic delta subunit* / cholinergic receptor, nicotinic, delta polypeptide*ENSGALG0000000789930
CHRNG / cholinergic receptor nicotinic gamma subunit / P07510* / cholinergic receptor, nicotinic, gamma polypeptide*ENSGALG0000000790630
HTR3A / 5-hydroxytryptamine receptor 3A / P46098* / 5-hydroxytryptamine (serotonin) receptor 3A*ENSGALG0000000700425
HTR3C* / HTR3D* / HTR3E* / Q8WXA8* / A5X5Y0* / Q70Z44* / 5-hydroxytryptamine receptor 3D* / 5-hydroxytryptamine receptor 3C* / 5-hydroxytryptamine receptor 3E*ENSGALG0000002601515


Protein motifs (from Interpro)
Interpro ID Name
 IPR002394  Nicotinic acetylcholine receptor
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0001988 positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007271 synaptic transmission, cholinergic IEA
 biological_processGO:0007611 learning or memory IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0008306 associative learning IEA
 biological_processGO:0009409 response to cold IEA
 biological_processGO:0014061 regulation of norepinephrine secretion IEA
 biological_processGO:0030317 flagellated sperm motility IEA
 biological_processGO:0032094 response to food IEA
 biological_processGO:0032225 regulation of synaptic transmission, dopaminergic IEA
 biological_processGO:0032691 negative regulation of interleukin-1 beta production IEA
 biological_processGO:0032715 negative regulation of interleukin-6 production IEA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035094 response to nicotine IEA
 biological_processGO:0035095 behavioral response to nicotine IEA
 biological_processGO:0042110 T cell activation IEA
 biological_processGO:0042113 B cell activation IEA
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0042698 ovulation cycle IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0048149 behavioral response to ethanol IEA
 biological_processGO:0050727 regulation of inflammatory response IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0050804 modulation of chemical synaptic transmission IEA
 biological_processGO:0050808 synapse organization IEA
 biological_processGO:0050893 sensory processing IEA
 biological_processGO:0051247 positive regulation of protein metabolic process IEA
 biological_processGO:0060078 regulation of postsynaptic membrane potential IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0060112 generation of ovulation cycle rhythm IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0097061 dendritic spine organization IEA
 biological_processGO:0098815 modulation of excitatory postsynaptic potential IEA
 biological_processGO:0140059 dendrite arborization IEA
 biological_processGO:1900273 positive regulation of long-term synaptic potentiation IEA
 biological_processGO:1901214 regulation of neuron death IEA
 biological_processGO:1902004 positive regulation of amyloid-beta formation IEA
 biological_processGO:1904645 response to amyloid-beta IEA
 biological_processGO:1905906 regulation of amyloid fibril formation IEA
 biological_processGO:1905920 positive regulation of CoA-transferase activity IEA
 biological_processGO:2000463 positive regulation of excitatory postsynaptic potential IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0030425 dendrite IDA
 cellular_componentGO:0030673 axolemma IEA
 cellular_componentGO:0043204 perikaryon IDA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0022848 acetylcholine-gated cation-selective channel activity IEA


Pathways (from Reactome)
Pathway description
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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