ENSGALG00000004665


Gallus gallus
proteinKPNA7importnucleusnuclearactivityarmadilloimportin-alphaimportin-beta-bindingdomainarmadillo-likehelicalarmadillo-typefoldimportinsubunitalphaatypicalarmrepeatnls-bearingtransportporenucleoplasmcytoplasmcytosollocalizationsequencebindingtransportersignal

Features
Gene ID: ENSGALG00000004665
  
Biological name :KPNA7
  
Synonyms : karyopherin subunit alpha 7 / KPNA7
  
Possible biological names infered from orthology : A9QM74 / C0LLJ0 / Importin subunit alpha-8
  
Species: Gallus gallus
  
Chr. number: 14
Strand: -1
Band:
Gene start: 4329333
Gene end: 4335420
  
Corresponding Affymetrix probe sets: GgaAffx.2890.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000007421
NCBI entrez gene - 416488     See in Manteia.
RefSeq - XM_004945165
RefSeq - XM_414795
swissprot - E1BVP7
Ensembl - ENSGALG00000004665
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kpna7ENSDARG00000027169Danio rerio
 KPNA7ENSG00000185467Homo sapiens
 Kpna7ENSMUSG00000038770Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KPNA2 / importin subunit alpha-1 / P52292* / P52293* / Gm10184* / predicted pseudogene 10184* / karyopherin subunit alpha 2*ENSGALG0000000358460
KPNA4 / karyopherin subunit alpha 4 / O00629* / O35343* / karyopherin (importin) alpha 4*ENSGALG0000000954948
KPNA3 / karyopherin subunit alpha 3 / O00505* / O35344* / Importin subunit alpha-4 *ENSGALG0000001700948
KPNA5 / karyopherin subunit alpha 5 / O15131*ENSGALG0000001493743
KPNA6 / karyopherin subunit alpha 6 / O35345* / O60684* / Importin subunit alpha-7 *ENSGALG0000000338342
KPNA1 / Q5ZML1 / Importin subunit alpha-5 / P52294* / Q60960* / karyopherin subunit alpha 1*ENSGALG0000001442642


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR002652  Importin-alpha, importin-beta-binding domain
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR024931  Importin subunit alpha
 IPR032413  Atypical Arm repeat


Gene Ontology (GO)
macromolecule localizationestablishment of localizationcellular localizationmacromolecule localizationestablishment of localizationcellular localizationmacromolecule localizationestablishment of localizationcellular localizationmacromolecule localizationestablishment of localizationcellular localizationmacromolecule localizationestablishment of localizationcellular localizationmacromolecule localizationestablishment of localizationcellular localizationmacromolecule localizationestablishment of localizationcellular localizationmacromolecule localizationestablishment of localizationcellular localizationmacromolecule localizationestablishment of localizationcellular localizationmacromolecule localizationestablishment of localizationcellular localizationmacromolecule localizationmacromolecule localizationestablishment of localizationestablishment of localizationcellular localizationcellular localization
amide bindingprotein transporter activitynucleocytoplasmic carrier activityamide bindingprotein transporter activitynucleocytoplasmic carrier activityamide bindingprotein transporter activitynucleocytoplasmic carrier activityamide bindingprotein transporter activitynucleocytoplasmic carrier activityamide bindingprotein transporter activitynucleocytoplasmic carrier activityamide bindingprotein transporter activitynucleocytoplasmic carrier activityamide bindingprotein transporter activitynucleocytoplasmic carrier activityamide bindingprotein transporter activitynucleocytoplasmic carrier activityamide bindingprotein transporter activitynucleocytoplasmic carrier activityamide bindingprotein transporter activitynucleocytoplasmic carrier activityamide bindingamide bindingprotein transporter activityprotein transporter activitynucleocytoplasmic carrier activitynucleocytoplasmic carrier activity
cellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellcellorganelleorganelleprotein-containing complexprotein-containing complexmembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0006606 protein import into nucleus IEA
 biological_processGO:0006607 NLS-bearing protein import into nucleus IBA
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IBA
 cellular_componentGO:0005654 nucleoplasm IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0008139 nuclear localization sequence binding IBA
 molecular_functionGO:0008565 protein transporter activity IBA
 molecular_functionGO:0061608 nuclear import signal receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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