ENSGALG00000004948


Gallus gallus
hydrolaseGLAactivityprocessglycosidemetabolicfamilyglycosylcatabolicconservedsiteall-betaaldolase-typetimbarrelsuperfamilycarbohydrateoligosaccharideglycosylceramideextracellularregioncytoplasmlysosomegolgiapparatuscatalytichydrolyzingo-glycosylcompoundsalpha-galactosidasesignaling

Features
Gene ID: ENSGALG00000004948
  
Biological name :GLA
  
Synonyms : galactosidase alpha / GLA
  
Possible biological names infered from orthology : P06280
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 2034276
Gene end: 2039395
  
Corresponding Affymetrix probe sets: Gga.16916.1.S1_at (Chicken Array)   Gga.16916.2.S1_at (Chicken Array)   Gga.16916.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000007923
NCBI entrez gene - 422188     See in Manteia.
RefSeq - XM_420183
swissprot - E1BT44
Ensembl - ENSGALG00000004948
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 glaENSDARG00000036155Danio rerio
 GLAENSG00000102393Homo sapiens
 GlaENSMUSG00000031266Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NAGA / alpha-N-acetylgalactosaminidase / P17050* / Q9QWR8*ENSGALG0000001190050


Protein motifs (from Interpro)
Interpro ID Name
 IPR000111  Glycoside hydrolase family 27/36, conserved site
 IPR002241  Glycoside hydrolase, family 27
 IPR013780  Glycosyl hydrolase, all-beta
 IPR013785  Aldolase-type TIM barrel
 IPR017853  Glycoside hydrolase superfamily


Gene Ontology (GO)
primary metabolic processorganic substance metabolic processcatabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processprimary metabolic processorganic substance metabolic organic substance metabolic processcatabolic processcatabolic processnitrogen compound metabolic nitrogen compound metabolic processcellular metabolic processcellular metabolic process
hydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityhydrolase activityprotein bindingprotein binding
extracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regionextracellular regioncellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009311 oligosaccharide metabolic process IEA
 biological_processGO:0016139 glycoside catabolic process IBA
 biological_processGO:0046477 glycosylceramide catabolic process IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEA
 molecular_functionGO:0004557 alpha-galactosidase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004948 GLA / galactosidase alpha / P06280*  / complex






 

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