ENSGALG00000005305


Gallus gallus
receptorACKR2chemokinemembraneactivityrhodopsin-likesignalg-proteincoupledsignalingpathwayplasmaintegralcomponentc-cgprotein-coupledfamilyatypicalgpcrtmreceptor-mediatedendocytosischemotaxisinflammatoryresponsetransductionchemokine-mediatednucleoplasmcytosolactin

Features
Gene ID: ENSGALG00000005305
  
Biological name :ACKR2
  
Synonyms : ACKR2 / atypical chemokine receptor 2
  
Possible biological names infered from orthology : O00590 / O08707
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 2096559
Gene end: 2103345
  
Corresponding Affymetrix probe sets: Gga.10342.1.S1_s_at (Chicken Array)   GgaAffx.26468.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000008492
swissprot - F1P1U9
Ensembl - ENSGALG00000005305
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ACKR2ENSG00000144648Homo sapiens
 Ackr2ENSMUSG00000044534Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCR4 / C-C motif chemokine receptor 4 / P51679* / P51680* / C-C chemokine receptor type 4 *ENSGALG0000003914632
CCR8L / C-C chemokine receptor 8 like / CCR8* / P51685* / P56484* / C-C motif chemokine receptor 8* / C-C chemokine receptor type 8 *ENSGALG0000001173430
CCR5 / CCR1* / CCR3* / CCR2* / P51681* / P41597* / P51675* / P51676* / P51677* / P51678* / P51682* / P51683* / Ccr1l1* / P32246* / C-C motif chemokine receptor 3* / C-C chemokine receptor t...ENSGALG0000003707729
CCR2 / C-C chemokine receptor type 2 / CCR1* / CCR5* / CCR3* / P51681* / P51683* / P51675* / P51676* / P51677* / P51678* / P51682* / Ccr1l1* / P32246* / P41597* / C-C motif chemokine recep...ENSGALG0000001173328
CCR8 / C-C motif chemokine receptor 8 / P51685* / P56484* / C-C chemokine receptor type 8 *ENSGALG0000003806928
CCR6 / C-C chemokine receptor type 6 / O54689* / P51684* / C-C motif chemokine receptor 6* / Mus musculus chemokine (C-C motif) receptor 6 (Ccr6), transcript variant 7, mRNA.*ENSGALG0000001141827
CX3CR1 / C-X3-C motif chemokine receptor 1 / P49238* / Q9Z0D9* / CX3C chemokine receptor 1 *ENSGALG0000003800027
CCR9 / C-C chemokine receptor type 9 / P51686* / Q9WUT7* / C-C motif chemokine receptor 9*ENSGALG0000001180825
CXCR4 / C-X-C motif chemokine receptor 4 / P61073* / Mus musculus chemokine (C-X-C motif) receptor 4 (Cxcr4), transcript variant 2, mRNA.*ENSGALG0000001235725
CCR10 / C-C motif chemokine receptor 10 / P46092* / Q9JL21* / C-C chemokine receptor type 10 *ENSGALG0000002851925
CCR7 / C-C motif chemokine receptor 7 / P32248* / P47774* / C-C chemokine receptor type 7 *ENSGALG0000003573325
CXCR1 / CXCR2* / Q810W6* / P25024* / P25025* / P35343* / C-X-C chemokine receptor type 1 * / C-X-C motif chemokine receptor 2* / C-X-C motif chemokine receptor 1* / C-X-C chemokine receptor type 2 *ENSGALG0000003662725
ACKR4 / atypical chemokine receptor 4 / Q924I3* / Q9NPB9*ENSGALG0000004149125
XCR1 / X-C motif chemokine receptor 1 / P46094* / chemokine (C motif) receptor 1*ENSGALG0000001173523
CXCR5 / C-X-C motif chemokine receptor 5 / P32302* / Q04683* / C-X-C chemokine receptor type 5 *ENSGALG0000000767522


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000355  Chemokine receptor family
 IPR005383  Atypical chemokine receptor 4
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
establishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell communicationcellular response to stimulusestablishment of localiestablishment of localizationresponse to external stresponse to external stimulusresponse to chemicalresponse to chemicalresponse to stressresponse to stresscell communicationcell communicationcellular response to stcellular response to stimulus
signaling receptor activityscavenger receptor activityprotein bindingsignaling receptor activityscavenger receptor activityprotein bindingsignaling receptor activityscavenger receptor activityprotein bindingsignaling receptor activityscavenger receptor activityprotein bindingsignaling receptor activityscavenger receptor activityprotein bindingsignaling receptor activityscavenger receptor activityprotein bindingsignaling receptor activityscavenger receptor activityprotein bindingsignaling receptor activityscavenger receptor activityprotein bindingsignaling receptor activityscavenger receptor activityprotein bindingsignaling receptor activityscavenger receptor activityprotein bindingsignaling receptor activitysignaling receptor activityscavenger receptor activityscavenger receptor activityprotein bindingprotein binding
cellorganellemembrane-enclosed lumensupramolecular complexmembranecellorganellemembrane-enclosed lumensupramolecular complexmembranecellorganellemembrane-enclosed lumensupramolecular complexmembranecellorganellemembrane-enclosed lumensupramolecular complexmembranecellorganellemembrane-enclosed lumensupramolecular complexmembranecellorganellemembrane-enclosed lumensupramolecular complexmembranecellorganellemembrane-enclosed lumensupramolecular complexmembranecellorganellemembrane-enclosed lumensupramolecular complexmembranecellorganellemembrane-enclosed lumensupramolecular complexmembranecellorganellemembrane-enclosed lumensupramolecular complexmembranecellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumensupramolecular complexsupramolecular complexmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005884 actin filament IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004950 chemokine receptor activity IEA
 molecular_functionGO:0005044 scavenger receptor activity IEA
 molecular_functionGO:0016493 C-C chemokine receptor activity IEA
 molecular_functionGO:0019957 C-C chemokine binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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