ENSGALG00000006357


Gallus gallus

Features
Gene ID: ENSGALG00000006357
  
Biological name :XPC
  
Synonyms : XPC / XPC complex subunit, DNA damage recognition and repair factor
  
Possible biological names infered from orthology : P51612 / Q01831 / xeroderma pigmentosum, complementation group C
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 10801221
Gene end: 10810412
  
Corresponding Affymetrix probe sets: Gga.13897.1.S1_at (Chicken Array)   Gga.13897.1.S1_x_at (Chicken Array)   GgaAffx.21910.1.S1_at (Chicken Array)   GgaAffx.3971.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010261
NCBI entrez gene - 416039     See in Manteia.
RefSeq - XM_015293355
RefSeq - XM_414379
swissprot - E1BUG1
Ensembl - ENSGALG00000006357
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 xpcENSDARG00000039754Danio rerio
 XPCENSG00000154767Homo sapiens
 XpcENSMUSG00000030094Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004583  DNA repair protein Rad4
 IPR018026  DNA repair protein Rad4, subgroup
 IPR018325  Rad4/PNGase transglutaminase-like fold
 IPR018326  Rad4 beta-hairpin domain 1
 IPR018327  Rad4 beta-hairpin domain 2
 IPR018328  Rad4 beta-hairpin domain 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000715 nucleotide-excision repair, DNA damage recognition IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006289 nucleotide-excision repair IBA
 biological_processGO:0006298 mismatch repair IBA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0010224 response to UV-B IEA
 biological_processGO:0031573 intra-S DNA damage checkpoint IEA
 biological_processGO:0070914 UV-damage excision repair IEA
 biological_processGO:1901990 regulation of mitotic cell cycle phase transition IEA
 cellular_componentGO:0000111 nucleotide-excision repair factor 2 complex IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0071942 XPC complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003684 damaged DNA binding IBA
 molecular_functionGO:0003697 single-stranded DNA binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of DNA damage response and repair proteins
DNA Damage Recognition in GG-NER
Formation of Incision Complex in GG-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007971 SUMO2 / Q5ZJM9 / Small ubiquitin-related modifier 2 / SUMO4* / Q6EEV6* / P61957* / P61956* / small ubiquitin-like modifier 2* / small ubiquitin-like modifier 4*  / complex
 ENSGALG00000008559 CUL4B / cullin 4B / A2A432* / Q13620*  / complex / reaction
 ENSGALG00000008218 DDB2 / Q5ZJL7 / DNA damage-binding protein 2 / Q92466* / Q99J79* / damage specific DNA binding protein 2*  / complex / reaction
 ENSGALG00000007510 CETN2 / CETN1* / Q9R1K9* / P41209* / Q12798* / P41208* / centrin 2* / centrin 1*  / complex / reaction
 ENSGALG00000008435 SUMO1 / Q8QGH2 / Small ubiquitin-related modifier 1 / P63166* / P63165* / small ubiquitin-like modifier 1*  / complex / reaction
 ENSGALG00000011993 RBX1 / ring-box 1 / P62877* / P62878* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000042333 DDB1 / Q805F9 / DNA damage-binding protein 1 / Q16531* / Q3U1J4* / damage specific DNA binding protein 1*  / complex / reaction
 ENSGALG00000009228 PARP1 / poly / P09874* / poly(ADP-ribose) polymerase 1* / poly (ADP-ribose) polymerase family, member 1*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction
 ENSGALG00000006428 UBE2I / P63283 / SUMO-conjugating enzyme UBC9 / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction






 

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