ENSGALG00000007141


Gallus gallus

Features
Gene ID: ENSGALG00000007141
  
Biological name :LRRK1
  
Synonyms : leucine rich repeat kinase 1 / LRRK1
  
Possible biological names infered from orthology : Leucine-rich repeat serine/threonine-protein kinase 1 / Q38SD2 / Q3UHC2
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 17531543
Gene end: 17565924
  
Corresponding Affymetrix probe sets: Gga.15094.1.S1_at (Chicken Array)   Gga.15283.1.S1_s_at (Chicken Array)   GgaAffx.22159.1.S1_at (Chicken Array)   GgaAffx.4474.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000011551
NCBI entrez gene - 415520     See in Manteia.
RefSeq - XM_003641822
swissprot - F1N8P0
Ensembl - ENSGALG00000007141
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrrk1ENSDARG00000007398Danio rerio
 LRRK1ENSG00000154237Homo sapiens
 Lrrk1ENSMUSG00000015133Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRRK2 / leucine-rich repeat serine/threonine-protein kinase 2 / Q5S006* / Q5S007* / leucine rich repeat kinase 2*ENSGALG0000000716122
PRKD1 / protein kinase D1 / Q15139* / Q62101*ENSGALG0000000990010
PRKD3 / protein kinase D3 / O94806* / Q8K1Y2*ENSGALG000000106129


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001611  Leucine-rich repeat
 IPR011009  Protein kinase-like domain superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR020859  Roc domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR032171  C-terminal of Roc (COR) domain
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0036035 osteoclast development IEA
 biological_processGO:0045453 bone resorption IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0050732 negative regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:1902533 positive regulation of intracellular signal transduction IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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