ENSGALG00000007462


Gallus gallus

Features
Gene ID: ENSGALG00000007462
  
Biological name :CTSZ
  
Synonyms : cathepsin Z / CTSZ
  
Possible biological names infered from orthology : Q9UBR2 / Q9WUU7
  
Species: Gallus gallus
  
Chr. number: 20
Strand: 1
Band:
Gene start: 11097473
Gene end: 11102231
  
Corresponding Affymetrix probe sets: GgaAffx.22250.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012053
Ensembl peptide - ENSGALP00000061000
Ensembl peptide - ENSGALP00000051470
NCBI entrez gene - 419311     See in Manteia.
RefSeq - XM_417483
swissprot - E1C4M3
swissprot - A0A1L1RQC1
swissprot - A0A1D5PFA7
Ensembl - ENSGALG00000007462
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctszENSDARG00000043081Danio rerio
 CTSZENSG00000101160Homo sapiens
 CtszENSMUSG00000016256Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CTSC / Gallus gallus cathepsin C (CTSC), mRNA. / P53634* / P97821* / cathepsin C*ENSGALG0000001723931
TINAG / tubulointerstitial nephritis antigen / Q9UJW2*ENSGALG0000001630024
CTSB / cathepsin B / P07858* / P10605*ENSGALG0000003001624
TINAGL1 / tubulointerstitial nephritis antigen like 1 / Q99JR5* / Q9GZM7* / Tubulointerstitial nephritis antigen-like *ENSGALG0000001771523
CTSO / cathepsin O / P43234* / Q8BM88*ENSGALG0000000937321


Protein motifs (from Interpro)
Interpro ID Name
 IPR000668  Peptidase C1A, papain C-terminal
 IPR013128  Peptidase C1A
 IPR025661  Cysteine peptidase, asparagine active site
 IPR033157  Cathepsin X


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0010757 negative regulation of plasminogen activation IEA
 biological_processGO:0032091 negative regulation of protein binding IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IBA
 biological_processGO:0060441 epithelial tube branching involved in lung morphogenesis IEA
 biological_processGO:1901214 regulation of neuron death IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0099738 cell cortex region IEA
 molecular_functionGO:0004180 carboxypeptidase activity IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IBA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA


Pathways (from Reactome)
Pathway description
Metabolism of Angiotensinogen to Angiotensins
COPII-mediated vesicle transport
Lysosome Vesicle Biogenesis
Cargo concentration in the ER
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000011117 AGT / angiotensinogen / P01019*  / reaction
 ENSGALG00000034821 LMAN1 / protein ERGIC-53 precursor / P49257* / Q9D0F3* / Protein ERGIC-53 * / lectin, mannose binding 1*  / complex / reaction






 

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