ENSGALG00000008060


Gallus gallus

Features
Gene ID: ENSGALG00000008060
  
Biological name :PRKAR2B
  
Synonyms : PRKAR2B / protein kinase cAMP-dependent type II regulatory subunit beta
  
Possible biological names infered from orthology : P31323 / P31324 / protein kinase, cAMP dependent regulatory, type II beta
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 14466581
Gene end: 14547811
  
Corresponding Affymetrix probe sets: GgaAffx.5055.2.S1_at (Chicken Array)   GgaAffx.5055.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013072
NCBI entrez gene - 769420     See in Manteia.
RefSeq - XM_015275787
RefSeq - XM_015275788
swissprot - F1NC65
Ensembl - ENSGALG00000008060
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRKAR2BENSDARG00000036446Danio rerio
 P31323ENSG00000005249Homo sapiens
 P31324ENSMUSG00000002997Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRKAR2A / protein kinase cAMP-dependent type II regulatory subunit alpha / P13861* / protein kinase, cAMP dependent regulatory, type II alpha*ENSGALG0000000702365
PRKAR1B / protein kinase cAMP-dependent type I regulatory subunit beta / P12849* / P31321* / protein kinase, cAMP dependent regulatory, type I beta*ENSGALG0000000367534
Q5ZM91 / PRKAR1A / cAMP-dependent protein kinase type I-alpha regulatory subunit / Q9DBC7* / P10644* / protein kinase, cAMP dependent regulatory, type I, alpha* / protein kinase cAMP-depen...ENSGALG0000000423734


Protein motifs (from Interpro)
Interpro ID Name
 IPR000595  Cyclic nucleotide-binding domain
 IPR003117  cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain
 IPR012198  cAMP-dependent protein kinase regulatory subunit
 IPR014710  RmlC-like jelly roll fold
 IPR018488  Cyclic nucleotide-binding, conserved site
 IPR018490  Cyclic nucleotide-binding-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001932 regulation of protein phosphorylation IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0007612 learning IEA
 biological_processGO:2000480 negative regulation of cAMP-dependent protein kinase activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005952 cAMP-dependent protein kinase complex IEA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0043198 dendritic shaft IEA
 cellular_componentGO:0097546 ciliary base IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004862 cAMP-dependent protein kinase inhibitor activity IEA
 molecular_functionGO:0008603 cAMP-dependent protein kinase regulator activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030552 cAMP binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0034236 protein kinase A catalytic subunit binding IEA


Pathways (from Reactome)
Pathway description
PKA activation
PKA activation in glucagon signalling
DARPP-32 events
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Vasopressin regulates renal water homeostasis via Aquaporins
Hedgehog off state
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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