ENSDARG00000036446


Danio rerio

Features
Gene ID: ENSDARG00000036446
  
Biological name :PRKAR2B
  
Synonyms : PRKAR2B / si:ch211-272n13.7
  
Possible biological names infered from orthology : P31323 / P31324 / protein kinase, cAMP dependent regulatory, type II beta / protein kinase cAMP-dependent type II regulatory subunit beta
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 3475384
Gene end: 3503458
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000142297
Ensembl peptide - ENSDARP00000148349
Ensembl peptide - ENSDARP00000152866
Ensembl peptide - ENSDARP00000154977
swissprot - A0A140LGB8
ZFIN ID - ZDB-GENE-160113-22
Ensembl - ENSDARG00000036446
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRKAR2BENSGALG00000008060Gallus gallus
 P31323ENSG00000005249Homo sapiens
 P31324ENSMUSG00000002997Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prkar2aa / protein kinase, cAMP-dependent, regulatory, type II, alpha A / P13861* / PRKAR2A* / protein kinase, cAMP dependent regulatory, type II alpha* / protein kinase cAMP-dependent type...ENSDARG0000003318464
prkar2ab / protein kinase, cAMP-dependent, regulatory, type II, alpha, B / P13861* / PRKAR2A* / protein kinase cAMP-dependent type II regulatory subunit alpha*ENSDARG0000000947758
prkar1aa / protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) aENSDARG0000007612833
prkar1ab / protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b / Q9DBC7* / P10644* / PRKAR1A* / protein kinase, cAMP dependent regulatory, type I, a...ENSDARG0000010175532
prkar1b / protein kinase, cAMP-dependent, regulatory, type I, beta / P12849* / P31321* / protein kinase cAMP-dependent type I regulatory subunit beta*ENSDARG0000010380032


Protein motifs (from Interpro)
Interpro ID Name
 IPR000595  Cyclic nucleotide-binding domain
 IPR003117  cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain
 IPR012198  cAMP-dependent protein kinase regulatory subunit
 IPR014710  RmlC-like jelly roll fold
 IPR018488  Cyclic nucleotide-binding, conserved site
 IPR018490  Cyclic nucleotide-binding-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001932 regulation of protein phosphorylation IEA
 biological_processGO:0045859 regulation of protein kinase activity IEA
 cellular_componentGO:0005952 cAMP-dependent protein kinase complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0008603 cAMP-dependent protein kinase regulator activity IEA
 molecular_functionGO:0030552 cAMP binding IEA


Pathways (from Reactome)
Pathway description
PKA activation
PKA activation in glucagon signalling
DARPP-32 events
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Vasopressin regulates renal water homeostasis via Aquaporins
Hedgehog off state
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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