ENSDARG00000009477


Danio rerio

Features
Gene ID: ENSDARG00000009477
  
Biological name :prkar2ab
  
Synonyms : prkar2ab / protein kinase, cAMP-dependent, regulatory, type II, alpha, B
  
Possible biological names infered from orthology : P13861 / PRKAR2A / protein kinase, cAMP dependent regulatory, type II alpha / protein kinase cAMP-dependent type II regulatory subunit alpha
  
Species: Danio rerio
  
Chr. number: 22
Strand: 1
Band:
Gene start: 110158
Gene end: 130695
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000115860
NCBI entrez gene - 405894     See in Manteia.
RefSeq - NM_212958
RefSeq Peptide - NP_998123
swissprot - F1Q6C0
swissprot - Q6NW93
ZFIN ID - ZDB-GENE-040426-2427
Ensembl - ENSDARG00000009477
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRKAR2AENSGALG00000007023Gallus gallus
 P13861ENSG00000114302Homo sapiens
 Prkar2aENSMUSG00000032601Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prkar2aa / protein kinase, cAMP-dependent, regulatory, type II, alpha A / P13861* / PRKAR2A* / protein kinase, cAMP dependent regulatory, type II alpha* / protein kinase cAMP-dependent type...ENSDARG0000003318464
PRKAR2B / si:ch211-272n13.7 / P31324* / P31323* / protein kinase, cAMP dependent regulatory, type II beta* / protein kinase cAMP-dependent type II regulatory subunit beta*ENSDARG0000003644655
prkar1aa / protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) aENSDARG0000007612830
prkar1ab / protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b / Q9DBC7* / P10644* / PRKAR1A* / protein kinase, cAMP dependent regulatory, type I, a...ENSDARG0000010175530
prkar1b / protein kinase, cAMP-dependent, regulatory, type I, beta / P12849* / P31321* / protein kinase cAMP-dependent type I regulatory subunit beta*ENSDARG0000010380030


Protein motifs (from Interpro)
Interpro ID Name
 IPR000595  Cyclic nucleotide-binding domain
 IPR003117  cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain
 IPR012198  cAMP-dependent protein kinase regulatory subunit
 IPR014710  RmlC-like jelly roll fold
 IPR018488  Cyclic nucleotide-binding, conserved site
 IPR018490  Cyclic nucleotide-binding-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001932 regulation of protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0045859 regulation of protein kinase activity IEA
 cellular_componentGO:0005952 cAMP-dependent protein kinase complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0008603 cAMP-dependent protein kinase regulator activity IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0030552 cAMP binding IEA


Pathways (from Reactome)
Pathway description
PKA activation
PKA activation in glucagon signalling
DARPP-32 events
Vasopressin regulates renal water homeostasis via Aquaporins
Hedgehog off state
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000059549 akap10 / A kinase (PRKA) anchor protein 10 / O43572* / O88845* / A-kinase anchoring protein 10* / A-kinase anchor protein 10, mitochondrial *  / complex / reaction
 ENSDARG00000006062 akap1b / A kinase (PRKA) anchor protein 1b / AKAP1* / O08715* / Q92667* / A-kinase anchoring protein 1* / A-kinase anchor protein 1, mitochondrial *  / complex / reaction
 ENSDARG00000033184 prkar2aa / protein kinase, cAMP-dependent, regulatory, type II, alpha A / P13861* / PRKAR2A* / protein kinase, cAMP dependent regulatory, type II alpha* / protein kinase cAMP-dependent type...  / complex
 ENSDARG00000059125 prkacbb / protein kinase, cAMP-dependent, catalytic, beta b / P22694* / PRKACB* / protein kinase cAMP-activated catalytic subunit beta*  / complex
 ENSDARG00000009477 prkar2ab / protein kinase, cAMP-dependent, regulatory, type II, alpha, B / P13861* / PRKAR2A* / protein kinase cAMP-dependent type II regulatory subunit alpha*  / complex
 ENSDARG00000103800 prkar1b / protein kinase, cAMP-dependent, regulatory, type I, beta / P12849* / P31321* / protein kinase cAMP-dependent type I regulatory subunit beta*  / complex






 

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