ENSGALG00000008127


Gallus gallus

Features
Gene ID: ENSGALG00000008127
  
Biological name :SPI1
  
Synonyms : SPI1 / transcription factor PU.1
  
Possible biological names infered from orthology : P17433 / P17947 / Spi-1 proto-oncogene / spleen focus forming virus (SFFV) proviral integration oncogene
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 22949194
Gene end: 22970222
  
Corresponding Affymetrix probe sets: Gga.1313.1.S1_s_at (Chicken Array)   GgaAffx.20689.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013176
Ensembl peptide - ENSGALP00000047958
NCBI entrez gene - 395879     See in Manteia.
RefSeq - NM_205023
RefSeq - XM_015286975
RefSeq Peptide - NP_990354
swissprot - E1BZN0
swissprot - A0A1D5P5I9
Ensembl - ENSGALG00000008127
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spi1aENSDARG00000067797Danio rerio
 spi1bENSDARG00000000767Danio rerio
 SPI1ENSG00000066336Homo sapiens
 Spi1ENSMUSG00000002111Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPIC / Spi-C transcription factor / Q6P3D7* / Q8N5J4* / Transcription factor Spi-C *ENSGALG0000002720926


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR011991  ArsR-like helix-turn-helix domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001944 vasculature development IEA
 biological_processGO:0002320 lymphoid progenitor cell differentiation IEA
 biological_processGO:0002573 myeloid leukocyte differentiation IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0030098 lymphocyte differentiation IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030218 erythrocyte differentiation IEA
 biological_processGO:0030225 macrophage differentiation IEA
 biological_processGO:0030851 granulocyte differentiation IEA
 biological_processGO:0035019 somatic stem cell population maintenance IEA
 biological_processGO:0043011 myeloid dendritic cell differentiation IEA
 biological_processGO:0043966 histone H3 acetylation IEA
 biological_processGO:0044027 hypermethylation of CpG island IEA
 biological_processGO:0045347 negative regulation of MHC class II biosynthetic process IEA
 biological_processGO:0045646 regulation of erythrocyte differentiation IEA
 biological_processGO:0045814 negative regulation of gene expression, epigenetic IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060033 anatomical structure regression IEA
 biological_processGO:0061614 pri-miRNA transcription by RNA polymerase II IEA
 biological_processGO:0090241 negative regulation of histone H4 acetylation IEA
 biological_processGO:1902262 apoptotic process involved in blood vessel morphogenesis IEA
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0000982 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001047 core promoter binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0051525 NFAT protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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