ENSGALG00000008544


Gallus gallus

Features
Gene ID: ENSGALG00000008544
  
Biological name :SLC8A1
  
Synonyms : SLC8A1 / sodium/calcium exchanger 1 precursor
  
Possible biological names infered from orthology : P32418 / solute carrier family 8 member A1 / solute carrier family 8 (sodium/calcium exchanger), member 1
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 16328932
Gene end: 16398413
  
Corresponding Affymetrix probe sets: Gga.453.1.A1_at (Chicken Array)   Gga.453.1.S1_s_at (Chicken Array)   GgaAffx.22620.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050459
Ensembl peptide - ENSGALP00000013904
NCBI entrez gene - 395760     See in Manteia.
RefSeq - XM_015283450
RefSeq - XM_015283447
RefSeq - XM_015283448
RefSeq - XM_015283449
RefSeq - NM_001079473
RefSeq - XM_015283436
RefSeq - XM_015283437
RefSeq - XM_015283438
RefSeq - XM_015283439
RefSeq - XM_015283441
RefSeq - XM_015283442
RefSeq - XM_015283443
RefSeq - XM_015283444
RefSeq - XM_015283445
RefSeq - XM_015283446
RefSeq Peptide - NP_001072941
swissprot - F1NYZ4
swissprot - A0A1D5PCH0
Ensembl - ENSGALG00000008544
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc8a1aENSDARG00000013422Danio rerio
 slc8a1bENSDARG00000043406Danio rerio
 P32418ENSG00000183023Homo sapiens
 Slc8a1ENSMUSG00000054640Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SLC8A3 / solute carrier family 8 member A3 / P57103* / S4R2P9* / solute carrier family 8 (sodium/calcium exchanger), member 3*ENSGALG0000000940070
ADGRV1* / Q8VHN7* / Q8WXG9* / adhesion G protein-coupled receptor V1*ENSGALG000000435562
ADGRV1* / Q8VHN7* / Q8WXG9* / adhesion G protein-coupled receptor V1*ENSGALG000000320660


Protein motifs (from Interpro)
Interpro ID Name
 IPR001623  DnaJ domain
 IPR002987  Sodium/calcium exchanger, isoform 1
 IPR003644  Na-Ca exchanger/integrin-beta4
 IPR004836  Sodium/calcium exchanger protein
 IPR004837  Sodium/calcium exchanger membrane region
 IPR032452  Sodium/calcium exchanger domain, C-terminal extension


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006883 cellular sodium ion homeostasis IEA
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0030501 positive regulation of bone mineralization IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0035994 response to muscle stretch IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070509 calcium ion import IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0098719 sodium ion import across plasma membrane IEA
 biological_processGO:0098735 positive regulation of the force of heart contraction IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005432 calcium:sodium antiporter activity IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA
 molecular_functionGO:0030506 ankyrin binding IEA


Pathways (from Reactome)
Pathway description
Reduction of cytosolic Ca++ levels
Sodium/Calcium exchangers
Ion homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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