ENSGALG00000008591


Gallus gallus

Features
Gene ID: ENSGALG00000008591
  
Biological name :CACNB2
  
Synonyms : CACNB2 / calcium voltage-gated channel auxiliary subunit beta 2
  
Possible biological names infered from orthology : Q08289 / Q8CC27 / Voltage-dependent L-type calcium channel subunit beta-2
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 19149202
Gene end: 19371796
  
Corresponding Affymetrix probe sets: Gga.19497.1.S1_at (Chicken Array)   GgaAffx.5412.1.S1_s_at (Chicken Array)   GgaAffx.5412.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013972
Ensembl peptide - ENSGALP00000047211
NCBI entrez gene - 428420     See in Manteia.
RefSeq - XM_425981
RefSeq - XM_015282015
RefSeq - XM_015282016
RefSeq - XM_015282011
RefSeq - XM_015282012
RefSeq - XM_015282013
RefSeq - XM_015282014
swissprot - E1BZF6
swissprot - A0A1D5P3F6
Ensembl - ENSGALG00000008591
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cacnb2aENSDARG00000099045Danio rerio
 cacnb2bENSDARG00000055565Danio rerio
 CACNB2ENSG00000165995Homo sapiens
 Cacnb2ENSMUSG00000057914Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CACNB1 / calcium voltage-gated channel auxiliary subunit beta 1 / Q02641* / Q8R3Z5* / Voltage-dependent L-type calcium channel subunit beta-1 *ENSGALG0000002578823


Protein motifs (from Interpro)
Interpro ID Name
 IPR000584  Voltage-dependent calcium channel, L-type, beta subunit
 IPR001452  SH3 domain
 IPR005444  Voltage-dependent calcium channel, L-type, beta-2 subunit
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0007528 neuromuscular junction development IBA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0051928 positive regulation of calcium ion transport IEA
 biological_processGO:0070509 calcium ion import IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0086045 membrane depolarization during AV node cell action potential IEA
 biological_processGO:0086091 regulation of heart rate by cardiac conduction IEA
 biological_processGO:0098912 membrane depolarization during atrial cardiac muscle cell action potential IEA
 biological_processGO:1901385 regulation of voltage-gated calcium channel activity IBA
 cellular_componentGO:0005891 voltage-gated calcium channel complex IEA
 cellular_componentGO:1990454 L-type voltage-gated calcium channel complex IEA
 molecular_functionGO:0005245 voltage-gated calcium channel activity IEA
 molecular_functionGO:0008331 high voltage-gated calcium channel activity IEA
 molecular_functionGO:0051015 actin filament binding IEA
 molecular_functionGO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential IEA
 molecular_functionGO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential IEA


Pathways (from Reactome)
Pathway description
Presynaptic depolarization and calcium channel opening
Regulation of insulin secretion
Phase 0 - rapid depolarisation
Phase 2 - plateau phase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000005332 O73700 / CACNA1D / Voltage-dependent L-type calcium channel subunit alpha-1D / Q01668* / Q99246* / calcium voltage-gated channel subunit alpha1 D*  / complex






 

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