ENSGALG00000008734


Gallus gallus

Features
Gene ID: ENSGALG00000008734
  
Biological name :PCSK2
  
Synonyms : PCSK2 / proprotein convertase subtilisin/kexin type 2
  
Possible biological names infered from orthology : P16519 / P21661
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 11512295
Gene end: 11607100
  
Corresponding Affymetrix probe sets: Gga.2777.1.S1_at (Chicken Array)   Gga.2786.1.S1_at (Chicken Array)   Gga.9404.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014198
Ensembl peptide - ENSGALP00000053398
NCBI entrez gene - 395136     See in Manteia.
RefSeq - XM_004940214
swissprot - A0A1D5PKN7
swissprot - F1NUG0
Ensembl - ENSGALG00000008734
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcsk2ENSDARG00000019451Danio rerio
 PCSK2ENSG00000125851Homo sapiens
 Pcsk2ENSMUSG00000027419Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FURIN / furin, paired basic amino acid cleaving enzyme / P09958* / P23188*ENSGALG0000000834132
PCSK1 / proprotein convertase subtilisin/kexin type 1 / P29120* / P63239* / Neuroendocrine convertase 1 *ENSGALG0000001468131
PCSK6 / proprotein convertase subtilisin/kexin type 6 / P29122*ENSGALG0000003007629
PCSK5* / Q04592* / Q92824* / proprotein convertase subtilisin/kexin type 5*ENSGALG0000003325629
PCSK4 / proprotein convertase subtilisin/kexin type 4 / P29121* / Q6UW60*ENSGALG0000002638427
PCSK7 / proprotein convertase subtilisin/kexin type 7 / Q16549* / Q61139*ENSGALG0000002922024
PCSK5* / Q04592* / Q92824* / proprotein convertase subtilisin/kexin type 5*ENSGALG000000151641


Protein motifs (from Interpro)
Interpro ID Name
 IPR000209  Peptidase S8/S53 domain
 IPR002884  P domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR015500  Peptidase S8, subtilisin-related
 IPR022398  Peptidase S8, subtilisin, His-active site
 IPR023827  Peptidase S8, subtilisin, Asp-active site
 IPR023828  Peptidase S8, subtilisin, Ser-active site
 IPR032815  Peptidase S8, pro-domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0016485 protein processing IEA
 biological_processGO:0016486 peptide hormone processing IEA
 biological_processGO:0016540 protein autoprocessing IEA
 biological_processGO:0030070 insulin processing IEA
 biological_processGO:0034230 enkephalin processing IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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