ENSGALG00000008858


Gallus gallus

Features
Gene ID: ENSGALG00000008858
  
Biological name :MDH1
  
Synonyms : Malate dehydrogenase, cytoplasmic / MDH1 / Q5ZME2
  
Possible biological names infered from orthology : malate dehydrogenase 1 / P14152 / P40925
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 9522514
Gene end: 9533431
  
Corresponding Affymetrix probe sets: Gga.1141.1.S1_at (Chicken Array)   GgaAffx.11545.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014374
Ensembl peptide - ENSGALP00000064296
Ensembl peptide - ENSGALP00000061808
Ensembl peptide - ENSGALP00000056972
Ensembl peptide - ENSGALP00000053696
Ensembl peptide - ENSGALP00000051015
NCBI entrez gene - 421281     See in Manteia.
RefSeq - NM_001316891
RefSeq - NM_001006395
RefSeq Peptide - NP_001006395
RefSeq Peptide - NP_001303820
swissprot - A0A1D5PE17
swissprot - A0A1L1RZK2
swissprot - Q5ZME2
swissprot - A0A1L1RSM7
swissprot - A0A1D5PVK0
swissprot - A0A1D5PLH9
Ensembl - ENSGALG00000008858
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mdh1aaENSDARG00000017772Danio rerio
 mdh1abENSDARG00000103849Danio rerio
 MDH1ENSG00000014641Homo sapiens
 Mdh1ENSMUSG00000020321Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MDH1B / malate dehydrogenase 1B / Q5F204* / Q5I0G3* / Putative malate dehydrogenase 1B *ENSGALG0000000854828


Protein motifs (from Interpro)
Interpro ID Name
 IPR001236  Lactate/malate dehydrogenase, N-terminal
 IPR001252  Malate dehydrogenase, active site
 IPR001557  L-lactate/malate dehydrogenase
 IPR010945  Malate dehydrogenase, type 2
 IPR011274  Malate dehydrogenase, NAD-dependent, cytosolic
 IPR015955  Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
 IPR016040  NAD(P)-binding domain
 IPR022383  Lactate/malate dehydrogenase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0006107 oxaloacetate metabolic process IBA
 biological_processGO:0006108 malate metabolic process IEA
 biological_processGO:0006734 NADH metabolic process IBA
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0043209 myelin sheath IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016615 malate dehydrogenase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0030060 L-malate dehydrogenase activity IEA


Pathways (from Reactome)
Pathway description
Gluconeogenesis
Gluconeogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008858 MDH1 / Q5ZME2 / Malate dehydrogenase, cytoplasmic / P14152* / P40925* / malate dehydrogenase 1*  / complex






 

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