ENSGALG00000009480


Gallus gallus

Features
Gene ID: ENSGALG00000009480
  
Biological name :DOCK4
  
Synonyms : dedicator of cytokinesis 4 / DOCK4
  
Possible biological names infered from orthology : Dedicator of cytokinesis protein 4 / P59764 / Q8N1I0
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 27184787
Gene end: 27262852
  
Corresponding Affymetrix probe sets: GgaAffx.5969.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000038075
NCBI entrez gene - 417779     See in Manteia.
RefSeq - XM_004937545
RefSeq - XM_004937546
RefSeq - XM_015282398
RefSeq - XM_416024
RefSeq - XM_004937544
swissprot - F1NKB3
Ensembl - ENSGALG00000009480
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dock4bENSDARG00000024874Danio rerio
 si:dkey-81e3.1ENSDARG00000076213Danio rerio
 DOCK4ENSG00000128512Homo sapiens
 Dock4ENSMUSG00000035954Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DOCK3 / dedicator of cytokinesis 3 / Q8IZD9*ENSGALG0000000233558
DOCK2 / dedicator of cytokinesis 2 / Q8C3J5* / Q92608* / Dedicator of cytokinesis protein 2 *ENSGALG0000000208033
DOCK1 / dedicator of cytokinesis 1 / Q14185* / Q8BUR4* / Dedicator of cytokinesis protein 1 *ENSGALG0000004225933
DOCK5* / B2RY04* / Q9H7D0* / dedicator of cytokinesis 5* / Dedicator of cytokinesis protein 5 *ENSGALG0000000031131


Protein motifs (from Interpro)
Interpro ID Name
 IPR010703  Dedicator of cytokinesis, C-terminal
 IPR016024  Armadillo-type fold
 IPR026791  Dedicator of cytokinesis
 IPR027357  DHR-2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:1904694 negative regulation of vascular smooth muscle contraction IEA
 biological_processGO:1904754 positive regulation of vascular associated smooth muscle cell migration IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032420 stereocilium IEA
 cellular_componentGO:0032421 stereocilium bundle IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IEA
 molecular_functionGO:0048365 Rac GTPase binding IEA


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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