ENSGALG00000010395


Gallus gallus

Features
Gene ID: ENSGALG00000010395
  
Biological name :SIAH2
  
Synonyms : SIAH2 / siah E3 ubiquitin protein ligase 2
  
Possible biological names infered from orthology : O43255 / Q06986
  
Species: Gallus gallus
  
Chr. number: 9
Strand: 1
Band:
Gene start: 23714328
Gene end: 23719075
  
Corresponding Affymetrix probe sets: Gga.6286.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000016911
NCBI entrez gene - 429164     See in Manteia.
RefSeq - XM_426719
swissprot - E1C3Q9
Ensembl - ENSGALG00000010395
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 siah2lENSDARG00000044381Danio rerio
 SIAH2ENSG00000181788Homo sapiens
 Siah2ENSMUSG00000036432Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SIAH1 / siah E3 ubiquitin protein ligase 1 / Siah1b* / Q8IUQ4* / P61092* / Siah1a* / siah E3 ubiquitin protein ligase 1B* / E3 ubiquitin-protein ligase SIAH1A *ENSGALG0000000391668
SIAH3 / siah E3 ubiquitin protein ligase family member 3 / Q8IW03*ENSGALG0000002684933


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR004162  E3 ubiquitin-protein ligase SIN-like
 IPR008974  TRAF-like
 IPR013010  Zinc finger, SIAH-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018121  Seven-in-absentia protein, TRAF-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0044257 cellular protein catabolic process IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008909 USP13 / ubiquitin carboxyl-terminal hydrolase 13 / Q92995* / Q5BKP2* / ubiquitin specific peptidase 13* / ubiquitin specific peptidase 13 (isopeptidase T-3)*  / complex / reaction






 

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