ENSGALG00000010402


Gallus gallus

Features
Gene ID: ENSGALG00000010402
  
Biological name :HPGDS
  
Synonyms : Hematopoietic prostaglandin D synthase / HPGDS / O73888
  
Possible biological names infered from orthology : O60760 / Q9JHF7
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 37449944
Gene end: 37475301
  
Corresponding Affymetrix probe sets: Gga.15142.1.S1_s_at (Chicken Array)   Gga.3137.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000062839
Ensembl peptide - ENSGALP00000016919
NCBI entrez gene - 395863     See in Manteia.
RefSeq - NM_205011
RefSeq Peptide - NP_990342
swissprot - A0A1L1RVH7
swissprot - O73888
swissprot - R9PXN7
Ensembl - ENSGALG00000010402
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HPGDSENSG00000163106Homo sapiens
 HpgdsENSMUSG00000029919Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GSTAL3 / glutathione S-transferase 3 / Gsta4* / P24472* / Glutathione S-transferase A4 *ENSGALG0000001632229
GSTA3 / Q08392 / Glutathione S-transferase / GSTA2* / GSTA1* / GSTA5* / P30115* / P08263* / P09210* / P10648* / P13745* / Gm3776* / Q16772* / Q7RTV2* / Gm10639* / predicted gene 3776* / Gl...ENSGALG0000001632528
GSTA2 / Q08393 / Glutathione S-transferase ENSGALG0000001632828
GSTA2* / GSTA1* / GSTA3* / GSTA5* / P13745* / P30115* / Q7RTV2* / P08263* / P09210* / P10648* / Gm3776* / Q16772* / Gm10639* / predicted gene 3776* / Glutathione S-transferase A2 * / Glutat...ENSGALG0000003865227
GSTA4LENSGALG0000001632426
GSTA2* / GSTA1* / GSTA3* / GSTA5* / P13745* / P30115* / Q7RTV2* / P08263* / P09210* / P10648* / Gm3776* / Q16772* / Gm10639* / predicted gene 3776* / Glutathione S-transferase A2 * / Glutat...ENSGALG0000002855126


Protein motifs (from Interpro)
Interpro ID Name
 IPR004045  Glutathione S-transferase, N-terminal
 IPR004046  Glutathione S-transferase, C-terminal
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR012336  Thioredoxin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001516 prostaglandin biosynthetic process IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0006693 prostaglandin metabolic process ISS
 biological_processGO:2000255 negative regulation of male germ cell proliferation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004364 glutathione transferase activity IEA
 molecular_functionGO:0004667 prostaglandin-D synthase activity ISS
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Glutathione conjugation
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000010402 HPGDS / O73888 / Hematopoietic prostaglandin D synthase / O60760* / Q9JHF7*  / complex






 

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